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Envelope-to: daisuke@saraya.co.in
Delivery-date: Thu, 02 Mar 2023 09:05:18 +0800
Message-ID: <1139915849334.1119371711477.1237888709.0.472000JL.2002@synd.ccsend.com>
Date: Wed, 1 Mar 2023 20:04:20 -0500 (EST)
From: ACROBiosystems <apac@acrobiosystems.com>
Reply-To: apac@acrobiosystems.com
To: daisuke@saraya.co.in
Subject: =?utf-8?Q?Cathepsin_B_For_AGLink=C2=AE_ADC_Site-specific_conjugation_kit?=
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View as Webpage Products Support Resources Insights About Us Cathepsin B Fo=
r AGLink=C2=AE ADC Site-specific conjugation kit Various factors during dev=
elopment can affect the efficacy of antibody-drug conjugates (ADCs), among =
which conjugation technology is a very important factor. A site-specific co=
njugation method precisely controls the conjugation site, producing a homog=
enous mixture, which is an especially promising path to improving ADC desig=
n. ACROBiosystems utilize AGLink=C2=AE site-specific conjugation kit to per=
form site-specific enzymatic modification of IgG Fc glycans and evaluate AD=
C conjugation homogeneity and cytotoxicity. Features >> Site-specific conju=
gation through Fc-glycans with high conjugation efficiency. >> Uniform DAR =
value that result in a highly homogeneous ADC products. >> Universal and ef=
ficient: Eliminate amino acid sequence evaluations. >> Easy to use: One-pot=
 conjugation method. Product List Cat. No. Product Description Size ADC-P00=
1 AGlink ADC Conjugation Kit (MMAE, DAR4) 1 Reaction, 2mg antibody conjugat=
ion ADC-P002 AGlink ADC Conjugation Kit (MMAE, DAR2) 1 Reaction, 2mg antibo=
dy conjugation Inquiry now Learn more here Verification data The Linker con=
tained in the kit can be cleavaged by Cathepsin B=EF=BC=8CACROBiosystems ca=
n provide high quality Cathepsin B proteases to Evaluate the effect of prot=
eases cleavage of linker to ensure the efficient release of the intracellul=
ar payloads.   Features >> Natural conformation: HEK293 expressed protein t=
o ensure the natural structure; >> High enzyme activity: enzyme activity > =
2,500 pmol/min/=C2=B5g. More proteases for peptide linker MMPs PLAU(upA) Pl=
asma Kallikrein/KLKB1 To receive the latest industry news and updates from =
ACROBiosystems, =EF=BB=BFvisit our website & follow us on our social media!=
=EF=BB=BF =E2=80=8A Visit our Website       ACROBiosystems | 1 Innovation W=
ay, Newark, DE 19711 Unsubscribe daisuke@saraya.co.in Update Profile | Our =
Privacy Policy | Constant Contact Data Notice Sent by apac@acrobiosystems.c=
om
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-V2l19dxgnEGWm0IbH0Gvr05-8mC6NyGz4oooUq6jhTu9Zj0aWauW3StRXZ5JJtkecjNim2Z4sP=
03bblFo38yYy5mLUqk1QVS-8Q=3D&c=3DHhYmK5eVI-n54aiLASa9gmwnjFVYXB_1fluX3BdBAJ=
-sXUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw5dTaxtnKOjOVUYq-4Gn=
Byg=3D=3D" target=3D"_blank" style=3D"font-size: 13px; color: rgb(255, 255,=
 255); text-decoration: underline; font-weight: bold;">About Us</a></p></td=
> </tr> </table> </td> </tr> </table> <table class=3D"layout layout--featur=
e layout--1-column" style=3D"background-color: #c03e30; table-layout: fixed=
;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" bgcolor=
=3D"#c03e30"> <tr> <td class=3D"column column--1 scale stack" style=3D"widt=
h: 100%;" align=3D"center" valign=3D"top">
<table class=3D"text text--feature text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"text-align: center; font-family: Arial,Verdana,Helvetica,sans-serif; co=
lor: #3E3E3E; font-size: 14px; line-height: 1.2; display: block; word-wrap:=
 break-word; padding: 10px 40px;" align=3D"center" valign=3D"top"><p style=
=3D"text-align: center; margin: 0;" align=3D"center"><span style=3D"font-si=
ze: 18px; font-weight: bold; color: rgb(255, 255, 255);">Cathepsin B For AG=
Link&#xae; ADC Site-specific conjugation kit</span></p></td> </tr> </table>=
 </td> </tr> </table> <table class=3D"layout layout--feature layout--1-colu=
mn" style=3D"table-layout: fixed; background-color: #F1F1F1;" width=3D"100%=
" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" bgcolor=3D"#F1F1F1"> <tr=
> <td class=3D"column column--1 scale stack" style=3D"width: 100%;" align=
=3D"center" valign=3D"top">
<table class=3D"text text--feature text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"line-height: 1.5; text-align: center; font-family: Arial,Verdana,Helvet=
ica,sans-serif; color: #3E3E3E; font-size: 14px; display: block; word-wrap:=
 break-word; padding: 10px 40px;" align=3D"center" valign=3D"top">
<p style=3D"text-align: left; margin: 0;" align=3D"left"><span style=3D"col=
or: black;">Various factors during development can affect the efficacy of a=
ntibody-drug conjugates (ADCs), among which conjugation technology is a ver=
y important factor. A site-specific conjugation method precisely controls t=
he conjugation site, producing a homogenous mixture, which is an especially=
 promising path to improving ADC design. ACROBiosystems utilize </span><a h=
ref=3D"https://r20.rs6.net/tn.jsp?f=3D0014eQBMdSDsPszyWgAK3TD8k134DNBAOAW5I=
rzLGKUx66Fl5sopuQQOEtKQibQTOdl3Gub3N1N1n0hPfkoU3VrdrvAQO46aT7-BpTGXTwHAWVCt=
BB68dSKnq7piKQ_lpbRmVjV8OtxqQ7AX0e33wkDgEAx6QqUz5buFhYY3ImIKTn_4_njGxHLvSxu=
BzXYbsr04yxZ4X4LkDG8VfadIKgmMbPfivaLCTc8NOwuL_Jdy7LFlXIwNZfs3F3lCj8HuphTx9O=
9pLTPR-zYOYowh6sRBMHCg-xEwjY3paKIZrNOBeIOIyRQtcC1rKc14t-0_f-8nG4JAYpatWm0Z0=
-S8BRL-6rCBXf3mVM1hY10mqiKV74=3D&c=3DHhYmK5eVI-n54aiLASa9gmwnjFVYXB_1fluX3B=
dBAJ-sXUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw5dTaxtnKOjOVUYq=
-4GnByg=3D=3D" target=3D"_blank" style=3D"color: rgb(192, 0, 0); font-weigh=
t: bold; text-decoration: none;">AGLink&#xae; site-specific conjugation kit=
</a><span style=3D"color: black;"> to perform site-specific enzymatic modif=
ication of IgG Fc glycans and evaluate ADC conjugation homogeneity and cyto=
toxicity.</span></p>
<p style=3D"text-align: left; margin: 0;" align=3D"left"><br></p>
<p style=3D"text-align: center; margin: 0;" align=3D"center"><span style=3D=
"color: black; font-weight: bold; font-size: 14px;">Features</span></p>
<p style=3D"text-align: left; margin: 0;" align=3D"left"><span style=3D"col=
or: black; font-size: 12px;">&gt;&gt; Site-specific conjugation through Fc-=
glycans with high conjugation efficiency.</span></p>
<p style=3D"text-align: left; margin: 0;" align=3D"left"><span style=3D"col=
or: black; font-size: 12px;">&gt;&gt; Uniform DAR value that result in a hi=
ghly homogeneous ADC products.</span></p>
<p style=3D"text-align: left; margin: 0;" align=3D"left"><span style=3D"col=
or: black; font-size: 12px;">&gt;&gt; Universal and efficient: Eliminate am=
ino acid sequence evaluations.</span></p>
<p style=3D"text-align: left; margin: 0;" align=3D"left"><span style=3D"col=
or: black; font-size: 12px;">&gt;&gt; Easy to use: One-pot conjugation meth=
od.</span></p>
<p style=3D"text-align: left; margin: 0;" align=3D"left"><br></p>
</td> </tr> </table> </td> </tr> </table> <table class=3D"layout layout--1-=
column" style=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cellpadd=
ing=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 scale stack=
" style=3D"width: 100%;" align=3D"center" valign=3D"top">
<table class=3D"text text--article text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"line-height: 1.5; text-align: left; font-family: Arial,Verdana,Helvetic=
a,sans-serif; color: #343332; font-size: 16px; display: block; word-wrap: b=
reak-word; padding: 10px 40px;" align=3D"left" valign=3D"top"><p style=3D"t=
ext-align: center; margin: 0;" align=3D"center"><span style=3D"font-family:=
 Calibri, Helvetica, Arial, sans-serif; font-weight: bold;">Product List</s=
pan></p></td> </tr> </table> </td> </tr> </table> <table class=3D"layout la=
yout--1-column" style=3D"table-layout: fixed;" width=3D"100%" border=3D"0" =
cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 sca=
le stack" style=3D"width: 100%;" align=3D"center" valign=3D"top">
<table class=3D"text text--dataTable text--padding-vertical" width=3D"100%"=
 border=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fi=
xed;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" styl=
e=3D"text-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; col=
or: #3E3E3E; font-size: 14px; line-height: 1.2; display: block; word-wrap: =
break-word; padding: 10px 40px;" align=3D"left" valign=3D"top" data-purpose=
=3D"dataTable"><div class=3D"dataTable dataTable--outerBorder dataTable--in=
nerBorder"> <table class=3D"dataTable_content" style=3D"background-color: #=
ffffff; width: 100%; min-width: 100%; border-collapse: collapse; font-famil=
y: Arial,Verdana,Helvetica,sans-serif; color: #3E3E3E; font-size: 14px; bor=
der: 1px solid #a6a6a6;" width=3D"100%" border=3D"0" cellpadding=3D"0" cell=
spacing=3D"0" bgcolor=3D"#ffffff">  <tr>  <td class=3D"dataTable_content-ce=
ll" style=3D"background-color: #c03e30; text-align: center; vertical-align:=
 top; padding: 10px; border: 1px solid #a6a6a6;" align=3D"center" bgcolor=
=3D"#c03e30" valign=3D"top"> <p style=3D"margin: 0;"><span style=3D"color: =
rgb(255, 255, 255);">Cat. No.</span></p> </td>  <td class=3D"dataTable_cont=
ent-cell" style=3D"background-color: #c03e30; text-align: center; vertical-=
align: top; padding: 10px; border: 1px solid #a6a6a6;" align=3D"center" bgc=
olor=3D"#c03e30" valign=3D"top"> <p style=3D"margin: 0;"><span style=3D"col=
or: rgb(255, 255, 255);">Product Description</span></p> </td>  <td class=3D=
"dataTable_content-cell" style=3D"background-color: #c03e30; text-align: ce=
nter; vertical-align: top; padding: 10px; border: 1px solid #a6a6a6;" align=
=3D"center" bgcolor=3D"#c03e30" valign=3D"top"> <p style=3D"margin: 0;"><sp=
an style=3D"color: rgb(255, 255, 255);">Size</span></p> </td>  </tr>  <tr> =
 <td class=3D"dataTable_content-cell" style=3D"text-align: center; vertical=
-align: top; padding: 10px; border: 1px solid #a6a6a6;" align=3D"center" va=
lign=3D"top"> <p style=3D"margin: 0;"><a href=3D"https://r20.rs6.net/tn.jsp=
?f=3D0014eQBMdSDsPszyWgAK3TD8k134DNBAOAW5IrzLGKUx66Fl5sopuQQOGMu00Imk61Qjem=
Y78FQgV9pDT1XH0Q0XrMGgwCZMPKY52OHjrtPgu4ugR7sKHEIpFSxf1aqi8NyZNw71lKFfBwP5P=
RTkrB0y_2Xjt8MbitFotpzkk0-FaPalyLt1o9Xa8_DvESjjlxwomxlo1S_i6Dm-wrBU7YKa7tUv=
oy0ZVEBsBxQVWNlPppP5VG90mC_l2F9myYnGr9CxXQtXk17i7lNaGZk79BMirbpcEbhlr9Pwa7i=
OCUb7yU29Y5YI-tYHrqrmarG6oKwpTSwTjfnW3cnASV0ubAxsqtU7I_LFaADDTGqlyLqG2lY_0v=
gjN3p7UsWvZYrzW_BvD-xuBGieEc=3D&c=3DHhYmK5eVI-n54aiLASa9gmwnjFVYXB_1fluX3Bd=
BAJ-sXUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw5dTaxtnKOjOVUYq-=
4GnByg=3D=3D" target=3D"_blank" style=3D"text-decoration: underline; color:=
 #4d4d4d; font-weight: bold;">ADC-P001</a></p> </td>  <td class=3D"dataTabl=
e_content-cell" style=3D"text-align: center; vertical-align: top; padding: =
10px; border: 1px solid #a6a6a6;" align=3D"center" valign=3D"top"> <p style=
=3D"margin: 0;">AGlink ADC Conjugation Kit (MMAE, DAR4)</p> </td>  <td clas=
s=3D"dataTable_content-cell" style=3D"text-align: center; vertical-align: t=
op; padding: 10px; border: 1px solid #a6a6a6;" align=3D"center" valign=3D"t=
op"> <p style=3D"margin: 0;">1 Reaction, 2mg antibody conjugation
</p> </td>  </tr>  <tr>  <td class=3D"dataTable_content-cell" style=3D"text=
-align: center; vertical-align: top; padding: 10px; border: 1px solid #a6a6=
a6;" align=3D"center" valign=3D"top"> <p style=3D"margin: 0;"><a href=3D"ht=
tps://r20.rs6.net/tn.jsp?f=3D0014eQBMdSDsPszyWgAK3TD8k134DNBAOAW5IrzLGKUx66=
Fl5sopuQQOGMu00Imk61QjemY78FQgV9pDT1XH0Q0XrMGgwCZMPKY52OHjrtPgu4ugR7sKHEIpF=
Sxf1aqi8NyZNw71lKFfBwP5PRTkrB0y_2Xjt8MbitFotpzkk0-FaPalyLt1o9Xa8_DvESjjlxwo=
mxlo1S_i6Dm-wrBU7YKa7tUvoy0ZVEBsBxQVWNlPppP5VG90mC_l2F9myYnGr9CxXQtXk17i7lN=
aGZk79BMirbpcEbhlr9Pwa7iOCUb7yU29Y5YI-tYHrqrmarG6oKwpTSwTjfnW3cnASV0ubAxsqt=
U7I_LFaADDTGqlyLqG2lY_0vgjN3p7UsWvZYrzW_BvD-xuBGieEc=3D&c=3DHhYmK5eVI-n54ai=
LASa9gmwnjFVYXB_1fluX3BdBAJ-sXUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFm=
jC1_oKrw5dTaxtnKOjOVUYq-4GnByg=3D=3D" target=3D"_blank" style=3D"text-decor=
ation: underline; color: #4d4d4d; font-weight: bold;">ADC-P002</a></p> </td=
>  <td class=3D"dataTable_content-cell" style=3D"text-align: center; vertic=
al-align: top; padding: 10px; border: 1px solid #a6a6a6;" align=3D"center" =
valign=3D"top"> <p style=3D"margin: 0;">AGlink ADC Conjugation Kit (MMAE, D=
AR2)</p> </td>  <td class=3D"dataTable_content-cell" style=3D"text-align: c=
enter; vertical-align: top; padding: 10px; border: 1px solid #a6a6a6;" alig=
n=3D"center" valign=3D"top"> <p style=3D"margin: 0;">1 Reaction, 2mg antibo=
dy conjugation
</p> </td>  </tr>  </table> </div></td> </tr> </table> </td> </tr> </table>=
 <table class=3D"layout layout--2-column" style=3D"table-layout: fixed;" wi=
dth=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td cla=
ss=3D"column column--1 scale stack" style=3D"width: 50%;" align=3D"center" =
valign=3D"top"> <table class=3D"button button--padding-vertical" width=3D"1=
00%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout=
: fixed;"> <tr> <td class=3D"button_container content-padding-horizontal" a=
lign=3D"center" style=3D"padding: 10px 20px 10px 40px;">    <table class=3D=
"button_content-row" style=3D"width: inherit; border-radius: 7px; border-sp=
acing: 0; background-color: #999999; border: none;" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" bgcolor=3D"#999999"> <tr> <td class=3D"button_con=
tent-cell" style=3D"padding: 10px 15px;" align=3D"center"> <a class=3D"butt=
on_link" href=3D"https://r20.rs6.net/tn.jsp?f=3D0014eQBMdSDsPszyWgAK3TD8k13=
4DNBAOAW5IrzLGKUx66Fl5sopuQQOD9LjASHlQaOwOe4G2W2YuOh1b6Fi42S6XS-fBwMX7srykU=
QvqMuWVH_3Srad0O-0pfVtCpFCv-CrePZi3Pw7UmondGHlPfhJm38HtlPZFkKI5HXz59M0vfSTr=
n9vFTJRTWrffKZxMrRtyET4ido-ezNYSvOASBNAJ6RIBT0QBRbeClV2fqk1sKC__IXF8Qo4BsAG=
aGCOcgBfs316FjqFzk1VrajMzHga_tLvZIhYNOdRGB1OJYCAoU8VkrWx0gcnaGlwlhVCiVUFsmo=
MOj-Wy6tsEolScDPbyFyNyQrHuQ1oDDA0GzyCRs=3D&c=3DHhYmK5eVI-n54aiLASa9gmwnjFVY=
XB_1fluX3BdBAJ-sXUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw5dTax=
tnKOjOVUYq-4GnByg=3D=3D" data-trackable=3D"true" style=3D"color: #FFFFFF; f=
ont-family: Arial,Verdana,Helvetica,sans-serif; font-size: 16px; word-wrap:=
 break-word; font-weight: bold; text-decoration: none;">Inquiry now</a> </t=
d> </tr> </table>    </td> </tr> </table>   </td>  <td class=3D"column colu=
mn--2 scale stack" style=3D"width: 50%;" align=3D"center" valign=3D"top"> <=
table class=3D"button button--padding-vertical" width=3D"100%" border=3D"0"=
 cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <=
td class=3D"button_container content-padding-horizontal" align=3D"center" s=
tyle=3D"padding: 10px 40px 10px 20px;">    <table class=3D"button_content-r=
ow" style=3D"width: inherit; border-radius: 7px; border-spacing: 0; backgro=
und-color: #999999; border: none;" border=3D"0" cellpadding=3D"0" cellspaci=
ng=3D"0" bgcolor=3D"#999999"> <tr> <td class=3D"button_content-cell" style=
=3D"padding: 10px 15px;" align=3D"center"> <a class=3D"button_link" href=3D=
"https://r20.rs6.net/tn.jsp?f=3D0014eQBMdSDsPszyWgAK3TD8k134DNBAOAW5IrzLGKU=
x66Fl5sopuQQOEtKQibQTOdl3Gub3N1N1n0hPfkoU3VrdrvAQO46aT7-BpTGXTwHAWVCtBB68dS=
Knq7piKQ_lpbRmVjV8OtxqQ7AX0e33wkDgEAx6QqUz5buFhYY3ImIKTn_4_njGxHLvSxuBzXYbs=
r04yxZ4X4LkDG8VfadIKgmMbPfivaLCTc8NOwuL_Jdy7LFlXIwNZfs3F3lCj8HuphTx9O9pLTPR=
-zYOYowh6sRBMHCg-xEwjY3paKIZrNOBeIOIyRQtcC1rKc14t-0_f-8nG4JAYpatWm0Z0-S8BRL=
-6rCBXf3mVM1hY10mqiKV74=3D&c=3DHhYmK5eVI-n54aiLASa9gmwnjFVYXB_1fluX3BdBAJ-s=
XUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw5dTaxtnKOjOVUYq-4GnBy=
g=3D=3D" data-trackable=3D"true" style=3D"color: #FFFFFF; font-family: Aria=
l,Verdana,Helvetica,sans-serif; font-size: 16px; word-wrap: break-word; fon=
t-weight: bold; text-decoration: none;">Learn more here</a> </td> </tr> </t=
able>    </td> </tr> </table>   </td> </tr> </table> <table class=3D"layout=
 layout--1-column" style=3D"table-layout: fixed;" width=3D"100%" border=3D"=
0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 =
scale stack" style=3D"width: 100%;" align=3D"center" valign=3D"top">
<table class=3D"text text--article text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"text-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; colo=
r: #343332; font-size: 16px; line-height: 1.2; display: block; word-wrap: b=
reak-word; padding: 10px 40px;" align=3D"left" valign=3D"top"><p style=3D"t=
ext-align: center; margin: 0;" align=3D"center"><span style=3D"font-weight:=
 bold; font-family: Calibri, Helvetica, Arial, sans-serif; color: rgb(0, 0,=
 0); font-size: 17px;">Verification data</span></p></td> </tr> </table> </t=
d> </tr> </table> <table class=3D"layout layout--1-column" style=3D"table-l=
ayout: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D=
"0"> <tr> <td class=3D"column column--1 scale stack" style=3D"width: 100%;"=
 align=3D"center" valign=3D"top">
<table class=3D"text text--article text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"line-height: 1.5; text-align: left; font-family: Arial,Verdana,Helvetic=
a,sans-serif; color: #343332; font-size: 16px; display: block; word-wrap: b=
reak-word; padding: 10px 40px;" align=3D"left" valign=3D"top">
<p style=3D"margin: 0;">The Linker contained in the kit can be cleavaged by=
 <a href=3D"https://r20.rs6.net/tn.jsp?f=3D0014eQBMdSDsPszyWgAK3TD8k134DNBA=
OAW5IrzLGKUx66Fl5sopuQQOK-FkdTT3PAGicZzRU9VvNuDZANQYahgNMVfrXj70mv4uejixhf3=
h88CHKanO6mHBWqY89VkQxgPGwV-4vafYG_kSozkye0BcozBdUfSbaMMT7xqYKNzBR3W38EfdSZ=
aZ2_q5UJyWhUgFEaDRu1N9Hs93atfdGL89TB5NYZlOqPcej1h0tJ4pCWQ3w8fcfEyGbta4O1qbN=
qvTi6rPyr4jD1H-tUGFCLbweu3--G8iDw5G91puTyn6SS9_3hEt4zgkKj22t0AjzQSLP_SITQaH=
hd6lexcIg_QaVW0l0bdcDh6&c=3DHhYmK5eVI-n54aiLASa9gmwnjFVYXB_1fluX3BdBAJ-sXUr=
08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw5dTaxtnKOjOVUYq-4GnByg=
=3D=3D" target=3D"_blank" style=3D"color: rgb(192, 0, 0); text-decoration: =
underline; font-weight: bold;">Cathepsin B</a>&#xff0c;ACROBiosystems can pr=
ovide <a href=3D"https://r20.rs6.net/tn.jsp?f=3D0014eQBMdSDsPszyWgAK3TD8k13=
4DNBAOAW5IrzLGKUx66Fl5sopuQQOK-FkdTT3PAGicZzRU9VvNuDZANQYahgNMVfrXj70mv4uej=
ixhf3h88CHKanO6mHBWqY89VkQxgPGwV-4vafYG_kSozkye0BcozBdUfSbaMMT7xqYKNzBR3W38=
EfdSZaZ2_q5UJyWhUgFEaDRu1N9Hs93atfdGL89TB5NYZlOqPcej1h0tJ4pCWQ3w8fcfEyGbta4=
O1qbNqvTi6rPyr4jD1H-tUGFCLbweu3--G8iDw5G91puTyn6SS9_3hEt4zgkKj22t0AjzQSLP_S=
ITQaHhd6lexcIg_QaVW0l0bdcDh6&c=3DHhYmK5eVI-n54aiLASa9gmwnjFVYXB_1fluX3BdBAJ=
-sXUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw5dTaxtnKOjOVUYq-4Gn=
Byg=3D=3D" target=3D"_blank" style=3D"color: rgb(192, 0, 0); font-weight: b=
old; text-decoration: underline;">high quality Cathepsin B proteases</a> to=
 <span style=3D"font-weight: bold;">Evaluate the effect of proteases cleava=
ge of linker to ensure the efficient release of the intracellular payloads.=
</span></p>
<p style=3D"text-align: center; margin: 0;" align=3D"center"><span style=3D=
"font-weight: bold;">&#xa0;</span></p>
<p style=3D"text-align: center; margin: 0;" align=3D"center"><span style=3D=
"font-weight: bold;">Features</span></p>
<p style=3D"margin: 0;">&gt;&gt; Natural conformation: HEK293 expressed pro=
tein to ensure the natural structure;</p>
<p style=3D"margin: 0;">&gt;&gt; High enzyme activity: enzyme activity &gt;=
 2,500 pmol/min/&#xb5;g.</p>
<p style=3D"margin: 0;"><br></p>
<p style=3D"text-align: center; margin: 0;" align=3D"center"><span style=3D=
"font-weight: bold;">More proteases for peptide linker</span></p>
</td> </tr> </table> </td> </tr> </table> <table class=3D"layout layout--1-=
column" style=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cellpadd=
ing=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 scale stack=
" style=3D"width: 100%;" align=3D"center" valign=3D"top">
<table class=3D"text text--dataTable text--padding-vertical" width=3D"100%"=
 border=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fi=
xed;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" styl=
e=3D"text-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; col=
or: #3E3E3E; font-size: 14px; line-height: 1.2; display: block; word-wrap: =
break-word; padding: 10px 40px;" align=3D"left" valign=3D"top" data-purpose=
=3D"dataTable"><div class=3D"dataTable dataTable--outerBorder dataTable--in=
nerBorder"> <table class=3D"dataTable_content" style=3D"background-color: #=
ffffff; width: 100%; min-width: 100%; border-collapse: collapse; font-famil=
y: Arial,Verdana,Helvetica,sans-serif; color: #3E3E3E; font-size: 14px; bor=
der: 1px solid #a6a6a6;" width=3D"100%" border=3D"0" cellpadding=3D"0" cell=
spacing=3D"0" bgcolor=3D"#ffffff">  <tr>  <td class=3D"dataTable_content-ce=
ll" style=3D"background-color: #c03e30; text-align: center; vertical-align:=
 top; padding: 10px; border: 1px solid #a6a6a6;" align=3D"center" bgcolor=
=3D"#c03e30" valign=3D"top"> <p style=3D"margin: 0;"><a href=3D"https://r20=
.rs6.net/tn.jsp?f=3D0014eQBMdSDsPszyWgAK3TD8k134DNBAOAW5IrzLGKUx66Fl5sopuQQ=
OMgPrhcx7gbkZuUSSicF0peIBzWeUgz13ptMpB2VcPWdMXAy68hXtmLJQliE6I6UNpe2KjkVw9x=
kExtJ5kv_bJ65kSkLxfE0PK_lz5Uttb2_0XIjh-i4LI0be5SN_S7YshgsUGaptJ3D-yUyW0a8Ie=
b9ETs6_-rNoAIrKt5jVkt9MgUYul7kJbFAWk4ouWJdov4-e9cTBqS4USdvC1wrYCAm6xASGu9z_=
xhUDMPSNlPDnruIsIRXoK_YFRHGBTJng8ra63REEfzCZ8WLZcEWQI71aKj-kt7FsEY9XafGju_P=
Pi5jBtqt7O1rHmFD0Rs5qVLyVyt-rPSDcAX6yRpaZpg=3D&c=3DHhYmK5eVI-n54aiLASa9gmwn=
jFVYXB_1fluX3BdBAJ-sXUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw5=
dTaxtnKOjOVUYq-4GnByg=3D=3D" target=3D"_blank" style=3D"color: rgb(255, 255=
, 255); font-weight: bold; text-decoration: underline;">MMPs</a></p> </td> =
 <td class=3D"dataTable_content-cell" style=3D"background-color: #c03e30; t=
ext-align: center; vertical-align: top; padding: 10px; border: 1px solid #a=
6a6a6;" align=3D"center" bgcolor=3D"#c03e30" valign=3D"top"> <p style=3D"ma=
rgin: 0;"><a href=3D"https://r20.rs6.net/tn.jsp?f=3D0014eQBMdSDsPszyWgAK3TD=
8k134DNBAOAW5IrzLGKUx66Fl5sopuQQOMgPrhcx7gbkOKKS-WyEJEOcRSJEiLzOM0jDS7I8FoQ=
-bkLxkz8NLzvPwWZx3cdv7HAXjKoKD6AKHrSNC1bSALcCQrlTqwp-WRVJGugI-r6DbE0vq88PFr=
_Z2mw9YlJHVFRTIdU10d_VsI6zB2CzlNJNlsh3hjTNTLqAo2TKs9pltvmAZlIbq8DqoOMkjlh7W=
G_tujqrpjNahXWjFWvlj-lq2irbn-L2vL43B9y9KvPNW_zqZT2je_60nY7o3Z4Ub3dAMuMjO1M3=
eiooB7tO_ySMGIqPuXxMug=3D=3D&c=3DHhYmK5eVI-n54aiLASa9gmwnjFVYXB_1fluX3BdBAJ=
-sXUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw5dTaxtnKOjOVUYq-4Gn=
Byg=3D=3D" target=3D"_blank" style=3D"color: rgb(255, 255, 255); font-weigh=
t: bold; text-decoration: underline;">PLAU(upA)</a></p> </td>  <td class=3D=
"dataTable_content-cell" style=3D"background-color: #c03e30; text-align: ce=
nter; vertical-align: top; padding: 10px; border: 1px solid #a6a6a6;" align=
=3D"center" bgcolor=3D"#c03e30" valign=3D"top"> <p style=3D"margin: 0;"><a =
href=3D"https://r20.rs6.net/tn.jsp?f=3D0014eQBMdSDsPszyWgAK3TD8k134DNBAOAW5=
IrzLGKUx66Fl5sopuQQOCGxdYs4GSTHgVfnfsMc7ZqdO56yX2Pxm8VTnsI3N3UzI5PQotwAXpUb=
1oo13Gm-KR3pCzMzx5Xj_tyoeSqVQO6-cz1Fkzz3QuPLTIEyQRKpQ9UvEemA1xyWU4XDBOXkocx=
52Miw7zU31LsPC-jDaZRTTrgNf6V2cjLHkBarJu_TNR7CtZA4wk1Alcx-j1_G2zfAtg81r6QG5F=
LZ_JCApXv-BxPOavoiskfcntwp8itxVDOW_P9j-xLLC8m6sPYKCwqlOvaTbqjRWQpT6kyH--PTt=
-pdehc174KzcMnNM9Q0woWD-UEuoNUtMegafPD1eg=3D=3D&c=3DHhYmK5eVI-n54aiLASa9gmw=
njFVYXB_1fluX3BdBAJ-sXUr08FPJaA=3D=3D&ch=3DLZnvCLsRNcil6Qs1H7rckBFmjC1_oKrw=
5dTaxtnKOjOVUYq-4GnByg=3D=3D" target=3D"_blank" style=3D"color: rgb(255, 25=
5, 255); font-weight: bold; text-decoration: underline;">Plasma Kallikrein/=
KLKB1</a></p> </td>  </tr>  </table> </div></td> </tr> </table> </td> </tr>=
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