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From: ACROBiosystems <acrobio.apac@outlook.com>
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Subject: What's Your Take on Neuroscience
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View as Webpage Products Support Resources Insights About Us What's Your Ta=
ke on Neuroscience Amyotrophic lateral sclerosis (ALS) is a fatal neurodege=
nerative disorder with a median survival of 2 to 3 years from symptom onset=
. The most common clinical manifestation is weakness and atrophy of the mus=
cles in the hands, as if the body were gradually frozen. Click here to lear=
n more=F0=9F=91=89 Pathology, Epidemiology, Pathogenesis and Therapeutic Dr=
ugs of ALS Aneuro is the product line of ACRO that focuses on neuroscience.=
 We are providing you with high-quality SOD1 and TREM2 proteins for therape=
utic drug development for ALS. Product List Verification data =E2=98=85High=
 purity verified by SDS-PAGE =E2=80=8A Human SOD1, His Tag (Cat. No. SO1-H5=
148) on SDS-PAGE under reducing (R) condition. The gel was stained overnigh=
t with Coomassie Blue. The purity of the protein is greater than 97%. IHuma=
n TREM2, Fc Tag (Cat. No. TR2-H5254) on SDS-PAGE under reducing (R) conditi=
on. The gel was stained overnight with Coomassie Blue. The purity of the pr=
otein is greater than 95%. =E2=98=85 High bioactivity verified by ELISA and=
 BLI =E2=80=8A Immobilized Human TREM2, Fc Tag (Cat. No. TR2-H5254) at 1 =
=CE=BCg/mL (100 =CE=BCL/well) can bind Anti-TREM2 Antibody, Human IgG1 with=
 a linear range of 1-20 ng/mL (QC tested). Request for protocol Loaded Huma=
n TREM2, Fc Tag (Cat. No. TR2-H5254) on Protein A Biosensor, can bind Human=
 Apolipoprotein E, His Tag (Cat. No. APE-H5246) with an affinity constant o=
f 106 nM as determined in BLI assay (ForteBio Octet Red96e). Request for pr=
otocol We are launching a survey for customers who have used or are current=
ly using viral vectors for neural tracing in the neurobiology research. Sha=
re your ideas and comments with us and be rewarded with a free gift! We loo=
k forward to receiving your responses!   =EF=BC=9E=EF=BC=9EClick here to ac=
cess the questionnaire To receive the latest industry news and updates from=
 ACROBiosystems, =EF=BB=BFvisit our website & follow us on our social media=
!=EF=BB=BF =E2=80=8A Visit our Website       ACROBiosystems | 1 Innovation =
Way, Newark, DE 19711 Unsubscribe tfujikawa@saraya.co.in Update Profile | O=
ur Privacy Policy | Constant Contact Data Notice Sent by acrobio.apac@outlo=
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d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
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CJYVUyL01_uw=3D=3D&ch=3DNOn6oD0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8T=
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> </tr> </table> </td> </tr> </table> <table class=3D"layout layout--featur=
e layout--1-column" style=3D"background-color: #c03e30; table-layout: fixed=
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<table class=3D"text text--feature text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
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ze: 22px; color: rgb(255, 255, 255); font-family: Calibri, Helvetica, Arial=
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p></td> </tr> </table> </td> </tr> </table> <table class=3D"layout layout--=
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F1F1F1;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" bg=
color=3D"#F1F1F1"> <tr> <td class=3D"column column--1 scale stack" style=3D=
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order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"text-align: center; font-family: Arial,Verdana,Helvetica,sans-serif; co=
lor: #3E3E3E; font-size: 14px; line-height: 1.2; display: block; word-wrap:=
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<p style=3D"text-align: left; margin: 0;" align=3D"left"><span style=3D"fon=
t-family: Calibri, Helvetica, Arial, sans-serif;">Amyotrophic lateral scler=
osis (ALS) is a fatal neurodegenerative disorder with a median survival of =
2 to 3 years from symptom onset. The most common clinical manifestation is =
weakness and atrophy of the muscles in the hands, as if the body were gradu=
ally frozen.</span></p>
<p style=3D"text-align: left; margin: 0;" align=3D"left"><a href=3D"https:/=
/r20.rs6.net/tn.jsp?f=3D001AuRZWG2MSGIjPWmWYxZp_NiNuLCpgFSelqZogGH0ioOfbBTu=
yEQPY1vFPgGAuTVX8ZCOmSpC7CdIufTfc1N38cc_v6gU_-Lg2KnqwfRuk8a2yUWo8rSllsvDtcq=
vkNliUUBu5iVxCDqauO-6yStniq5sYGfNSgWtVaFz93Ut5DrMAzXf5AuJJ0YRerLxSIBig3g_oQ=
Ig3wTuCJbjbj3a_FjuOcVLTxHbUk59-Fc72ICPq4vOa_ILlF7VAzxf_GYzkpYV9fbZrdnaa0a1i=
tQo4VAawW3-x8fc-_4uYDJDFsH6IJf7EIt-b5zi5dyEPNDpRnl5x-8jKBbsw-Oa0rmEEM7Ez6y2=
dFRNgknOU2EeV88YzI0mdf8AZmJUXM4JQf8p4q06cI3G5gKaM9owzfCLBaIMer3_jX9WJDiYLf1=
8uGnCKndD7RjcQ9oqnk9kCtJa3jAb4TdDWnw=3D&c=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C=
6egECk58w0YCJYVUyL01_uw=3D=3D&ch=3DNOn6oD0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ=
3fgaNq1KE8Tziw=3D=3D" target=3D"_blank" style=3D"color: #B30000; font-weigh=
t: bold; text-decoration: none;">Click here to learn more&#x1f449; Patholog=
y, Epidemiology, Pathogenesis and Therapeutic Drugs of ALS</a></p>
<p style=3D"text-align: left; margin: 0;" align=3D"left"><span style=3D"fon=
t-family: Calibri, Helvetica, Arial, sans-serif;">Aneuro is the product lin=
e of ACRO that focuses on neuroscience. We are providing you with high-qual=
ity </span><a href=3D"https://r20.rs6.net/tn.jsp?f=3D001AuRZWG2MSGIjPWmWYxZ=
p_NiNuLCpgFSelqZogGH0ioOfbBTuyEQPY1vFPgGAuTVXz25ghW9zmhC-Y9l7iwYs_HG-B1-5yi=
L1KBR4rQeU_y38e6_A65vB4qeYoaY-Tr6IYG5vi0eCd5kgVEbCqFc9O5_wCLzCBUJSzelidfy5g=
nQlEzq8zBcUMqh3vSL8vlTmikryRCOijEnwAbbYoG-SZQQTthe0ZmHeANSsHtrzJKIPCmNoarcL=
o6S1RzE-f6IJ_3rhcK-UKGiCanmjE5JH5LzXrwY3vMYN1JLZw-lOVKqh_VB4YvoKANwDAsPD1-d=
EvKriR8g6lGSOIjGV4ePomA=3D=3D&c=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C6egECk58w0=
YCJYVUyL01_uw=3D=3D&ch=3DNOn6oD0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8=
Tziw=3D=3D" target=3D"_blank" style=3D"font-family: Calibri, Helvetica, Ari=
al, sans-serif; color: rgb(192, 0, 0); font-weight: bold; text-decoration: =
none;">SOD1</a><span style=3D"font-family: Calibri, Helvetica, Arial, sans-=
serif;"> and</span><a href=3D"https://r20.rs6.net/tn.jsp?f=3D001AuRZWG2MSGI=
jPWmWYxZp_NiNuLCpgFSelqZogGH0ioOfbBTuyEQPYzc425aXORNfAQ6dqhjwRDwjDmIeQoS7tY=
5G3bxBFXSDmlfYOmA2M3kZrQlXOBnQaQWsOdAHVnMCydT9EfrpKgEdwNiMCAFvsNSR5F9sfCjNE=
QzNMICa69S3TIjVz6-92-wJg8UnxfQOeUxb5niBsnH21DB123Q1Cfsxy0KM0MaEg2RoxH_2X7vw=
LTF5ZNPQfrDBcu_pudHtRx03vTYbjXPe0BHHAZfYp_rNpnPNdPsDx2Eym8-gDxiEwnwgrU5301W=
Ii_rfonwxo5VpN3l__aUGmGdFOu2IdQ=3D=3D&c=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C6e=
gECk58w0YCJYVUyL01_uw=3D=3D&ch=3DNOn6oD0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3f=
gaNq1KE8Tziw=3D=3D" target=3D"_blank" style=3D"font-family: Calibri, Helvet=
ica, Arial, sans-serif; color: rgb(192, 0, 0); font-weight: bold; text-deco=
ration: none;"> TREM2</a><span style=3D"font-family: Calibri, Helvetica, Ar=
ial, sans-serif;"> proteins for therapeutic drug development for ALS.</span=
></p>
</td> </tr> </table> </td> </tr> </table> <table class=3D"layout layout--1-=
column" style=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cellpadd=
ing=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 scale stack=
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<table class=3D"text text--article text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"line-height: 1.5; text-align: left; font-family: Arial,Verdana,Helvetic=
a,sans-serif; color: #343332; font-size: 16px; display: block; word-wrap: b=
reak-word; padding: 10px 40px;" align=3D"left" valign=3D"top"><p style=3D"t=
ext-align: center; margin: 0;" align=3D"center"><span style=3D"font-family:=
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pan></p></td> </tr> </table> </td> </tr> </table> <table class=3D"layout la=
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cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 sca=
le stack" style=3D"width: 100%;" align=3D"center" valign=3D"top">
<table class=3D"image image--padding-vertical image--mobile-scale image--mo=
bile-center" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0=
"> <tr> <td class=3D"image_container content-padding-horizontal" align=3D"c=
enter" valign=3D"top" style=3D"padding: 10px 40px;"> <a href=3D"https://r20=
.rs6.net/tn.jsp?f=3D001AuRZWG2MSGIjPWmWYxZp_NiNuLCpgFSelqZogGH0ioOfbBTuyEQP=
YzfmRGbYDiRW-5nBxyxxyZU4LH9v4pY7XGZflNGKV2BwHVXSFsJcLhQ-yWB0gl6rhfhhHR4_Vlr=
tfFCXnaxpETD4TV6BgUvmKFW2YNMh-s6CLO2-lQm_f01ot299gC4H0ukQ6mlKtBcnbBGO1YTolU=
lQWZPhRo3YAvhYxeUyA7UYZoKnts3e9meN4xCuZcta2UcW_eQ5KMFX4Zq7QbcQB61hAhUroUVKY=
Gec_4xHnTbW-WyptiWPHjITMozP5nPNTRULpX_tNplLvC2sNZhDQ0Uul7_5XOJ3C4LVpdFfs5Ii=
B0L5Z9VmC18=3D&c=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_uw=
=3D=3D&ch=3DNOn6oD0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" d=
ata-trackable=3D"true"><img data-image-content class=3D"image_content" widt=
h=3D"597" src=3D"https://files.constantcontact.com/5f3d0cf9401/beec01d7-f1a=
d-4471-a90e-746da7f52e98.png" alt=3D"" style=3D"display: block; height: aut=
o; max-width: 100%;"></a> </td> </tr> </table> </td> </tr> </table> <table =
class=3D"layout layout--1-column" style=3D"table-layout: fixed;" width=3D"1=
00%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"co=
lumn column--1 scale stack" style=3D"width: 100%;" align=3D"center" valign=
=3D"top">
<table class=3D"text text--article text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"text-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; colo=
r: #343332; font-size: 16px; line-height: 1.2; display: block; word-wrap: b=
reak-word; padding: 10px 40px;" align=3D"left" valign=3D"top"><p style=3D"t=
ext-align: center; margin: 0;" align=3D"center"><span style=3D"font-weight:=
 bold; font-family: Calibri, Helvetica, Arial, sans-serif; color: rgb(0, 0,=
 0); font-size: 17px;">Verification data</span></p></td> </tr> </table> </t=
d> </tr> </table> <table class=3D"layout layout--1-column" style=3D"table-l=
ayout: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D=
"0"> <tr> <td class=3D"column column--1 scale stack" style=3D"width: 100%;"=
 align=3D"center" valign=3D"top">
<table class=3D"text text--article text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"line-height: 1.5; text-align: left; font-family: Arial,Verdana,Helvetic=
a,sans-serif; color: #343332; font-size: 16px; display: block; word-wrap: b=
reak-word; padding: 10px 40px;" align=3D"left" valign=3D"top"><p style=3D"m=
argin: 0;"><span style=3D"font-weight: bold; font-family: Calibri, Helvetic=
a, Arial, sans-serif; font-size: 15px;">&#x2605;High purity verified by SDS=
-PAGE</span></p></td> </tr> </table> </td> </tr> </table> <table class=3D"l=
ayout-margin" style=3D"" width=3D"100%" border=3D"0" cellpadding=3D"0" cell=
spacing=3D"0"> <tr> <td class=3D"layout-margin_cell" style=3D"padding: 0px =
40px;" align=3D"center" valign=3D"top"> <table class=3D"layout layout--2-co=
lumn layout--divided" style=3D"table-layout: fixed;" width=3D"100%" border=
=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column=
-border column--1 scale stack" style=3D"width: 50%; border: 1px solid #3e3e=
3e;" align=3D"center" valign=3D"top">
<div class=3D"spacer" style=3D"line-height: 15px; height: 15px;">&#x200a;</=
div>
<table class=3D"image image--mobile-scale image--mobile-center" width=3D"10=
0%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"ima=
ge_container" align=3D"center" valign=3D"top"> <img data-image-content clas=
s=3D"image_content" width=3D"124" src=3D"https://files.constantcontact.com/=
5f3d0cf9401/08287299-d18d-4f50-b8e0-af4516ecdc52.jpg" alt=3D"" style=3D"dis=
play: block; height: auto; max-width: 100%;"> </td> </tr> </table> <table c=
lass=3D"text text--padding-vertical" width=3D"100%" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td class=3D=
"text_content-cell content-padding-horizontal" style=3D"line-height: 1.5; t=
ext-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; color: #3=
E3E3E; font-size: 14px; display: block; word-wrap: break-word; padding: 10p=
x 20px;" align=3D"left" valign=3D"top"><p style=3D"margin: 0;"><span style=
=3D"font-size: 12px; color: rgb(85, 85, 85); font-family: Calibri, Helvetic=
a, Arial, sans-serif;">Human SOD1, His Tag</span><span style=3D"font-size: =
12px; font-family: Calibri, Helvetica, Arial, sans-serif;"> </span><span st=
yle=3D"font-size: 11px; font-family: Calibri, Helvetica, Arial, sans-serif;=
">(Cat. No.</span><a href=3D"https://r20.rs6.net/tn.jsp?f=3D001AuRZWG2MSGIj=
PWmWYxZp_NiNuLCpgFSelqZogGH0ioOfbBTuyEQPY1vFPgGAuTVX9f5bFcC871fDLG0eBasOA8n=
_ZblLA4reAfAxFs-C-mDk9CyQW50fAoGrqCQHdFvwfY0q73YLRSKMJIFF0HtywwFgeGoow0rDnl=
h3kraGEPs58Iy6k0OxtFwmTN0QHOBFdQQ9RV0JtBqBVs6ay6OPCWygbMj9n9_6jCK94Qv6KKT4n=
lFGNof_yPKaoJots_2mBzAKYIG-T1BU17baSfGGLtgvuem7QVynjsicGlF20645GN6wNgy3iPu_=
S_sHbdrKG5MsBDs4bQIMNk0ohOe8LXcgaKmtZlP0NoPu_3JvecRflCVVuGXYNqKY6poK6V-2&c=
=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_uw=3D=3D&ch=3DNOn6oD=
0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" target=3D"_blank" s=
tyle=3D"font-size: 11px; font-family: Calibri, Helvetica, Arial, sans-serif=
; color: rgb(192, 62, 48); font-weight: bold; text-decoration: underline;">=
 SO1-H5148</a><span style=3D"font-size: 11px; font-family: Calibri, Helveti=
ca, Arial, sans-serif;">)</span><span style=3D"font-size: 12px; font-family=
: Calibri, Helvetica, Arial, sans-serif; color: rgb(85, 85, 85);"> on SDS-P=
AGE under reducing (R) condition. The gel was stained overnight with Coomas=
sie Blue. The purity of the protein is greater than </span><span style=3D"f=
ont-size: 12px; font-family: Calibri, Helvetica, Arial, sans-serif; color: =
rgb(192, 0, 0);">97%</span><span style=3D"font-size: 12px; font-family: Cal=
ibri, Helvetica, Arial, sans-serif; color: rgb(85, 85, 85);">.</span></p></=
td> </tr> </table> </td>  <td class=3D"column-divider scale stack" style=3D=
"height: 1px; line-height: 1px;" width=3D"20" align=3D"center" valign=3D"to=
p"> <img alt=3D"" width=3D"20" height=3D"20" border=3D"0" hspace=3D"0" vspa=
ce=3D"0" src=3D"https://imgssl.constantcontact.com/letters/images/110111678=
4221/S.gif"> </td>  <td class=3D"column column-border column--2 scale stack=
" style=3D"width: 50%; border: 1px solid #3e3e3e;" align=3D"center" valign=
=3D"top">
<table class=3D"image image--padding-vertical image--mobile-scale image--mo=
bile-center" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0=
"> <tr> <td class=3D"image_container" align=3D"center" valign=3D"top" style=
=3D"padding-top: 10px; padding-bottom: 10px;"> <img data-image-content clas=
s=3D"image_content" width=3D"116" src=3D"https://files.constantcontact.com/=
5f3d0cf9401/27605d06-5b5d-43ee-9b6a-d7531701356f.jpg" alt=3D"" style=3D"dis=
play: block; height: auto; max-width: 100%;"> </td> </tr> </table> <table c=
lass=3D"text text--padding-vertical" width=3D"100%" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td class=3D=
"text_content-cell content-padding-horizontal" style=3D"line-height: 1.5; t=
ext-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; color: #3=
E3E3E; font-size: 14px; display: block; word-wrap: break-word; padding: 10p=
x 20px;" align=3D"left" valign=3D"top"><p style=3D"text-align: center; marg=
in: 0;" align=3D"center"><span style=3D"color: black; font-family: Arial, V=
erdana, Helvetica, sans-serif;">I</span><span style=3D"color: rgb(85, 85, 8=
5); font-family: Calibri, Helvetica, Arial, sans-serif; font-size: 12px;">H=
uman TREM2, Fc Tag (Cat. No. </span><a href=3D"https://r20.rs6.net/tn.jsp?f=
=3D001AuRZWG2MSGIjPWmWYxZp_NiNuLCpgFSelqZogGH0ioOfbBTuyEQPYzc425aXORNfRHiNy=
BtZ3DRsYh0hV3jBh0_oQxzq0jx6tO6ZEHgJtDtluKhTUWmeZ6AYa-8MscICmRHg41xwMCywiJ3b=
E4381KfnDw1YUOCA6R9gl_b4QG3uJiJhjfV_fPj8Y59aF4DIbRiqkLzeTGtFzlssq0vnKPYsNpG=
PMu0b9toOivbCdmt6ZZNT-ZzbFIbCVW18FRZtS8AOkeWBMY1hTp0U5u_fWdac0bg0A7OUoxW_n2=
a388Ff0zwSKck__WXoo6UEEPaGIa6P6YQcr7OU-Z2L1BayXGefyTki11YalOy-sGrO1YA=3D&c=
=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_uw=3D=3D&ch=3DNOn6oD=
0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" target=3D"_blank" s=
tyle=3D"color: rgb(192, 0, 0); font-family: Calibri, Helvetica, Arial, sans=
-serif; font-size: 12px; font-weight: bold; text-decoration: underline;">TR=
2-H5254</a><span style=3D"color: rgb(85, 85, 85); font-family: Calibri, Hel=
vetica, Arial, sans-serif; font-size: 12px;">) on SDS-PAGE under reducing (=
R) condition. The gel was stained overnight with Coomassie Blue. The purity=
 of the protein is greater than</span><span style=3D"color: rgb(192, 0, 0);=
 font-family: Calibri, Helvetica, Arial, sans-serif; font-size: 12px;"> 95%=
</span><span style=3D"color: rgb(85, 85, 85); font-family: Calibri, Helveti=
ca, Arial, sans-serif; font-size: 12px;">.</span></p></td> </tr> </table> <=
/td> </tr> </table>  </td> </tr> </table> <table class=3D"layout layout--1-=
column" style=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cellpadd=
ing=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 scale stack=
" style=3D"width: 100%;" align=3D"center" valign=3D"top">
<table class=3D"text text--article text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"line-height: 1.5; text-align: left; font-family: Arial,Verdana,Helvetic=
a,sans-serif; color: #343332; font-size: 16px; display: block; word-wrap: b=
reak-word; padding: 10px 40px;" align=3D"left" valign=3D"top"><p style=3D"m=
argin: 0;"><span style=3D"font-size: 15px; font-family: Calibri, Helvetica,=
 Arial, sans-serif; font-weight: bold;">&#x2605;</span><span style=3D'font-=
size: 15px; font-family: Georgia, "Times New Roman", Times, serif;'>&#xa0;<=
/span><span style=3D"font-family: Calibri, Helvetica, Arial, sans-serif; fo=
nt-weight: bold; font-size: 15px;">High bioactivity verified by ELISA and B=
LI</span></p></td> </tr> </table> </td> </tr> </table> <table class=3D"layo=
ut-margin" style=3D"" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspa=
cing=3D"0"> <tr> <td class=3D"layout-margin_cell" style=3D"padding: 0px 40p=
x;" align=3D"center" valign=3D"top"> <table class=3D"layout layout--2-colum=
n layout--divided" style=3D"table-layout: fixed;" width=3D"100%" border=3D"=
0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column-bor=
der column--1 scale stack" style=3D"width: 50%; border: 1px solid #3e3e3e;"=
 align=3D"center" valign=3D"top">
<div class=3D"spacer" style=3D"line-height: 11px; height: 11px;">&#x200a;</=
div>
<table class=3D"image image--mobile-scale image--mobile-center" width=3D"10=
0%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"ima=
ge_container" align=3D"center" valign=3D"top"> <img data-image-content clas=
s=3D"image_content" width=3D"288" src=3D"https://files.constantcontact.com/=
5f3d0cf9401/a7f7b9ce-4355-4f99-925b-ba9912aa794a.jpg" alt=3D"" style=3D"dis=
play: block; height: auto; max-width: 100%;"> </td> </tr> </table> <table c=
lass=3D"text text--padding-vertical" width=3D"100%" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td class=3D=
"text_content-cell content-padding-horizontal" style=3D"line-height: 1.5; t=
ext-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; color: #3=
E3E3E; font-size: 14px; display: block; word-wrap: break-word; padding: 10p=
x 20px;" align=3D"left" valign=3D"top"><p style=3D"margin: 0;"><span style=
=3D"color: black; font-family: Calibri, Helvetica, Arial, sans-serif;">Immo=
bilized Human TREM2, Fc Tag (Cat. No. </span><a href=3D"https://r20.rs6.net=
/tn.jsp?f=3D001AuRZWG2MSGIjPWmWYxZp_NiNuLCpgFSelqZogGH0ioOfbBTuyEQPYzc425aX=
ORNfRHiNyBtZ3DRsYh0hV3jBh0_oQxzq0jx6tO6ZEHgJtDtluKhTUWmeZ6AYa-8MscICmRHg41x=
wMCywiJ3bE4381KfnDw1YUOCA6R9gl_b4QG3uJiJhjfV_fPj8Y59aF4DIbRiqkLzeTGtFzlssq0=
vnKPYsNpGPMu0b9toOivbCdmt6ZZNT-ZzbFIbCVW18FRZtS8AOkeWBMY1hTp0U5u_fWdac0bg0A=
7OUoxW_n2a388Ff0zwSKck__WXoo6UEEPaGIa6P6YQcr7OU-Z2L1BayXGefyTki11YalOy-sGrO=
1YA=3D&c=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_uw=3D=3D&ch=
=3DNOn6oD0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" target=3D"=
_blank" style=3D"color: rgb(192, 0, 0); font-family: Calibri, Helvetica, Ar=
ial, sans-serif; font-weight: bold; text-decoration: underline;">TR2-H5254<=
/a><span style=3D"color: black; font-family: Calibri, Helvetica, Arial, san=
s-serif;">) at 1 &#x3bc;g/mL (100 &#x3bc;L/well) can bind Anti-TREM2 Antibo=
dy, Human IgG1 with a linear range of 1-20 ng/mL (QC tested).</span></p></t=
d> </tr> </table>  <table class=3D"button button--padding-vertical" width=
=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-l=
ayout: fixed;"> <tr> <td class=3D"button_container content-padding-horizont=
al" align=3D"center" style=3D"padding: 10px 20px;">    <table class=3D"butt=
on_content-row" style=3D"width: inherit; border-radius: 7px; border-spacing=
: 0; background-color: #999999; border: none;" border=3D"0" cellpadding=3D"=
0" cellspacing=3D"0" bgcolor=3D"#999999"> <tr> <td class=3D"button_content-=
cell" style=3D"padding: 10px 15px;" align=3D"center"> <a class=3D"button_li=
nk" href=3D"https://r20.rs6.net/tn.jsp?f=3D001AuRZWG2MSGIjPWmWYxZp_NiNuLCpg=
FSelqZogGH0ioOfbBTuyEQPY3IoMYAXFw5xx-igE8tjCcAxviJpo2sCu2HMv29WgFiYJ1iq4fSj=
KgN1YEjwoHK_UoowOj9VE0Gvq21EaScvar_Rw2IfAtcXj8qkXNaz5BJz1ZbG6a7M1JlRF89lqEr=
PG_vf9EqwTylVhHJ2zQXXgeaXMpHksehEZyfu9FuBgX3-V3kR3YBrWZNXZTWjJJwizTjGcLuEin=
_hKZhxIPz2GA08OlrR8HUQT-zDRki4bHy_LjOsOBqDxNVpsy6dzOUdXj8-bJ7YwL_I1Rs3N9W5W=
xGhg7gllE99Rqs8DJoPXJv-fJtDSwhmR3hVMqfKCzFO5771pWiTh7B5&c=3Dx_NSuJwK1Gi4Z-c=
xfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_uw=3D=3D&ch=3DNOn6oD0pDyNU_1xviQCtzGN1=
GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" data-trackable=3D"true" style=3D"font=
-size: 12px; color: #FFFFFF; font-family: Arial,Verdana,Helvetica,sans-seri=
f; word-wrap: break-word; font-weight: bold; text-decoration: none;">Reques=
t for protocol</a> </td> </tr> </table>    </td> </tr> </table>   </td>  <t=
d class=3D"column-divider scale stack" style=3D"height: 1px; line-height: 1=
px;" width=3D"20" align=3D"center" valign=3D"top"> <img alt=3D"" width=3D"2=
0" height=3D"20" border=3D"0" hspace=3D"0" vspace=3D"0" src=3D"https://imgs=
sl.constantcontact.com/letters/images/1101116784221/S.gif"> </td>  <td clas=
s=3D"column column-border column--2 scale stack" style=3D"width: 50%; borde=
r: 1px solid #3e3e3e;" align=3D"center" valign=3D"top">
<table class=3D"image image--padding-vertical image--mobile-scale image--mo=
bile-center" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0=
"> <tr> <td class=3D"image_container" align=3D"center" valign=3D"top" style=
=3D"padding-top: 10px; padding-bottom: 10px;"> <img data-image-content clas=
s=3D"image_content" width=3D"263" src=3D"https://files.constantcontact.com/=
5f3d0cf9401/91accafc-4a00-4fbe-87e8-d243b00a8cd3.jpg" alt=3D"" style=3D"dis=
play: block; height: auto; max-width: 100%;"> </td> </tr> </table> <table c=
lass=3D"text text--padding-vertical" width=3D"100%" border=3D"0" cellpaddin=
g=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td class=3D=
"text_content-cell content-padding-horizontal" style=3D"line-height: 1.5; t=
ext-align: left; font-family: Arial,Verdana,Helvetica,sans-serif; color: #3=
E3E3E; font-size: 14px; display: block; word-wrap: break-word; padding: 10p=
x 20px;" align=3D"left" valign=3D"top"><p style=3D"margin: 0;"><span style=
=3D"color: black; font-family: Calibri, Helvetica, Arial, sans-serif;">Load=
ed Human TREM2, Fc Tag (Cat. No. </span><a href=3D"https://r20.rs6.net/tn.j=
sp?f=3D001AuRZWG2MSGIjPWmWYxZp_NiNuLCpgFSelqZogGH0ioOfbBTuyEQPYzc425aXORNfR=
HiNyBtZ3DRsYh0hV3jBh0_oQxzq0jx6tO6ZEHgJtDtluKhTUWmeZ6AYa-8MscICmRHg41xwMCyw=
iJ3bE4381KfnDw1YUOCA6R9gl_b4QG3uJiJhjfV_fPj8Y59aF4DIbRiqkLzeTGtFzlssq0vnKPY=
sNpGPMu0b9toOivbCdmt6ZZNT-ZzbFIbCVW18FRZtS8AOkeWBMY1hTp0U5u_fWdac0bg0A7OUox=
W_n2a388Ff0zwSKck__WXoo6UEEPaGIa6P6YQcr7OU-Z2L1BayXGefyTki11YalOy-sGrO1YA=
=3D&c=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_uw=3D=3D&ch=3DN=
On6oD0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" target=3D"_bla=
nk" style=3D"color: rgb(192, 0, 0); font-family: Calibri, Helvetica, Arial,=
 sans-serif; font-weight: bold; text-decoration: underline;">TR2-H5254</a><=
span style=3D"color: black; font-family: Calibri, Helvetica, Arial, sans-se=
rif;">) on Protein A Biosensor, can bind Human Apolipoprotein E, His Tag (C=
at. No. </span><a href=3D"https://r20.rs6.net/tn.jsp?f=3D001AuRZWG2MSGIjPWm=
WYxZp_NiNuLCpgFSelqZogGH0ioOfbBTuyEQPYzc425aXORNfFlv9F-dcoG7TXP6X15py02H2vl=
OBDtHTq7CUfn-NNltD0wsSwqQAN-WJ_Q4dnZ-pCyvB7MI29lqp8RwuGfPi0CAD8fSnnhXLkWWMI=
7Kkwm9-kDmr4J3advJEAvJlDB7hNhsXlEZ3N08O6UxmD8oXpu8iuZGbM8r9th8OeZCPHq5X9ZTP=
NQ1cVuZOwgAwJl-LVQxtr_WUWcSpqo7nk5ohPxdZmHFuwCUOJsimHRRIiuQyZycgyllPqz1jqLr=
UWIW-vLzd9h492Xs-jDFgVvrZFeLOLLOC7Lu2y0f3e-MsrUUfsXxc32wMltVbYhjLr38TFaIkCR=
5BG7c=3D&c=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_uw=3D=3D&c=
h=3DNOn6oD0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" target=3D=
"_blank" style=3D"color: rgb(192, 0, 0); font-family: Calibri, Helvetica, A=
rial, sans-serif; font-weight: bold; text-decoration: underline;">APE-H5246=
</a><span style=3D"color: black; font-family: Calibri, Helvetica, Arial, sa=
ns-serif;">) with an affinity constant of 106 nM as determined in BLI assay=
 (ForteBio Octet Red96e).</span></p></td> </tr> </table>  <table class=3D"b=
utton button--padding-vertical" width=3D"100%" border=3D"0" cellpadding=3D"=
0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td class=3D"butt=
on_container content-padding-horizontal" align=3D"center" style=3D"padding:=
 10px 20px;">    <table class=3D"button_content-row" style=3D"width: inheri=
t; border-radius: 7px; border-spacing: 0; background-color: #999999; border=
: none;" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" bgcolor=3D"#99999=
9"> <tr> <td class=3D"button_content-cell" style=3D"padding: 10px 15px;" al=
ign=3D"center"> <a class=3D"button_link" href=3D"https://r20.rs6.net/tn.jsp=
?f=3D001AuRZWG2MSGIjPWmWYxZp_NiNuLCpgFSelqZogGH0ioOfbBTuyEQPY3IoMYAXFw5xx-i=
gE8tjCcAxviJpo2sCu2HMv29WgFiYJ1iq4fSjKgN1YEjwoHK_UoowOj9VE0Gvq21EaScvar_Rw2=
IfAtcXj8qkXNaz5BJz1ZbG6a7M1JlRF89lqErPG_vf9EqwTylVhHJ2zQXXgeaXMpHksehEZyfu9=
FuBgX3-V3kR3YBrWZNXZTWjJJwizTjGcLuEin_hKZhxIPz2GA08OlrR8HUQT-zDRki4bHy_LjOs=
OBqDxNVpsy6dzOUdXj8-bJ7YwL_I1Rs3N9W5WxGhg7gllE99Rqs8DJoPXJv-fJtDSwhmR3hVMqf=
KCzFO5771pWiTh7B5&c=3Dx_NSuJwK1Gi4Z-cxfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_u=
w=3D=3D&ch=3DNOn6oD0pDyNU_1xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" =
data-trackable=3D"true" style=3D"font-size: 12px; color: #FFFFFF; font-fami=
ly: Arial,Verdana,Helvetica,sans-serif; word-wrap: break-word; font-weight:=
 bold; text-decoration: none;">Request for protocol</a> </td> </tr> </table=
>    </td> </tr> </table>   </td> </tr> </table>  </td> </tr> </table> <tab=
le class=3D"layout layout--1-column" style=3D"table-layout: fixed;" width=
=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=
=3D"column column--1 scale stack" style=3D"width: 100%;" align=3D"center" v=
align=3D"top">
<table class=3D"divider divider--dashed" width=3D"100%" cellpadding=3D"0" c=
ellspacing=3D"0" border=3D"0"> <tr> <td class=3D"divider_container content-=
padding-horizontal" style=3D"padding: 10px 40px;" width=3D"100%" align=3D"c=
enter" valign=3D"top"> <table class=3D"divider_content-row" style=3D"height=
: 1px; width: 100%;" cellpadding=3D"0" cellspacing=3D"0" border=3D"0"> <tr>=
 <td class=3D"divider_content-cell" style=3D"height: 1px; line-height: 1px;=
 padding-bottom: 0px; background-color: transparent; border-bottom-width: 1=
px; border-bottom-style: dashed; border-bottom-color: #4d4d4d;" height=3D"1=
" align=3D"center" bgcolor=3D"transparent"> <img alt=3D"" width=3D"5" heigh=
t=3D"1" border=3D"0" hspace=3D"0" vspace=3D"0" src=3D"https://imgssl.consta=
ntcontact.com/letters/images/1101116784221/S.gif" style=3D"display: block; =
height: 1px; width: 5px;"> </td> </tr> </table> </td> </tr> </table> </td> =
</tr> </table> <table class=3D"layout layout--1-column" style=3D"table-layo=
ut: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"=
> <tr> <td class=3D"column column--1 scale stack" style=3D"width: 100%;" al=
ign=3D"center" valign=3D"top">
<table class=3D"image image--padding-vertical image--mobile-scale image--mo=
bile-center" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0=
"> <tr> <td class=3D"image_container content-padding-horizontal" align=3D"c=
enter" valign=3D"top" style=3D"padding: 10px 40px;"> <a href=3D"https://r20=
.rs6.net/tn.jsp?f=3D001AuRZWG2MSGIjPWmWYxZp_NiNuLCpgFSelqZogGH0ioOfbBTuyEQP=
Y4k4uKCIqWXvV0D6DlGIvcnnEDJPkhoFF57-8xT99_18fLN01s_ytT7iOuWqPCBp3aG-WynWnM5=
0Sg2GXp4fhhsCD44_K4xujcWn5r0Wf1U1_ePmB8vfRC0jqlzrYEDRW2jQFWQwaHO375KOjtCJ7e=
4_sH56ZQvXzSIpwBu1rkhYWgkcc_HOrTRe2O26ejWfWkp0CQ2RcdXbkWUvDSh21s6j1yzyuF8iA=
90ClauNwHccu9-ZncSqGLPKCY3abhfSV-1sIf9QVz8m8M_YOaFFGHc=3D&c=3Dx_NSuJwK1Gi4Z=
-cxfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_uw=3D=3D&ch=3DNOn6oD0pDyNU_1xviQCtzG=
N1GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" data-trackable=3D"true"><img data-i=
mage-content class=3D"image_content" width=3D"586" src=3D"https://files.con=
stantcontact.com/5f3d0cf9401/6df28787-cdba-47b6-b655-f40085d1244d.jpg" alt=
=3D"" style=3D"display: block; height: auto; max-width: 100%;"></a> </td> <=
/tr> </table> </td> </tr> </table> <table class=3D"layout layout--1-column"=
 style=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"=
0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 scale stack" style=
=3D"width: 100%;" align=3D"center" valign=3D"top">
<table class=3D"text text--padding-vertical" width=3D"100%" border=3D"0" ce=
llpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td =
class=3D"text_content-cell content-padding-horizontal" style=3D"text-align:=
 left; font-family: Arial,Verdana,Helvetica,sans-serif; color: #3E3E3E; fon=
t-size: 14px; line-height: 1.2; display: block; word-wrap: break-word; padd=
ing: 10px 40px;" align=3D"left" valign=3D"top">
<p style=3D"margin: 0;"><span style=3D"font-family: Calibri, Helvetica, Ari=
al, sans-serif; color: black;">We are launching a survey for customers who =
have used or are currently using viral vectors for neural tracing in the ne=
urobiology research. Share your ideas and comments with us and be rewarded =
with a free gift! We look forward to receiving your responses!&#xa0;</span>=
</p>
<p style=3D"margin: 0;"><span style=3D'font-size: 9px; color: red; font-fam=
ily: Georgia, "Times New Roman", Times, serif;'>&#xa0;</span><a href=3D"htt=
ps://r20.rs6.net/tn.jsp?f=3D001AuRZWG2MSGIjPWmWYxZp_NiNuLCpgFSelqZogGH0ioOf=
bBTuyEQPY4k4uKCIqWXvV0D6DlGIvcnnEDJPkhoFF57-8xT99_18fLN01s_ytT7iOuWqPCBp3aG=
-WynWnM50Sg2GXp4fhhsCD44_K4xujcWn5r0Wf1U1_ePmB8vfRC0jqlzrYEDRW2jQFWQwaHO375=
KOjtCJ7e4_sH56ZQvXzSIpwBu1rkhYWgkcc_HOrTRe2O26ejWfWkp0CQ2RcdXbkWUvDSh21s6j1=
yzyuF8iA90ClauNwHccu9-ZncSqGLPKCY3abhfSV-1sIf9QVz8m8M_YOaFFGHc=3D&c=3Dx_NSu=
JwK1Gi4Z-cxfilHyxWN_tQS25C6egECk58w0YCJYVUyL01_uw=3D=3D&ch=3DNOn6oD0pDyNU_1=
xviQCtzGN1GJHgGVYWqVaxpjgJ3fgaNq1KE8Tziw=3D=3D" target=3D"_blank" style=3D"=
color: red; font-family: Arial, Verdana, Helvetica, sans-serif; text-decora=
tion: underline; font-weight: bold;">&#xff1e;&#xff1e;Click here to access t=
he questionnaire</a></p>
</td> </tr> </table> </td> </tr> </table> <table class=3D"layout layout--1-=
column" style=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cellpadd=
ing=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 scale stack=
" style=3D"width: 100%;" align=3D"center" valign=3D"top">
<table class=3D"divider divider--dashed" width=3D"100%" cellpadding=3D"0" c=
ellspacing=3D"0" border=3D"0"> <tr> <td class=3D"divider_container content-=
padding-horizontal" style=3D"padding: 10px 40px;" width=3D"100%" align=3D"c=
enter" valign=3D"top"> <table class=3D"divider_content-row" style=3D"height=
: 1px; width: 100%;" cellpadding=3D"0" cellspacing=3D"0" border=3D"0"> <tr>=
 <td class=3D"divider_content-cell" style=3D"height: 1px; line-height: 1px;=
 padding-bottom: 0px; background-color: transparent; border-bottom-width: 1=
px; border-bottom-style: dashed; border-bottom-color: #4d4d4d;" height=3D"1=
" align=3D"center" bgcolor=3D"transparent"> <img alt=3D"" width=3D"5" heigh=
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