관리-도구

편집 파일: 1670551131.M487441P7230.server.saraya-global.com,S=53093,W=53911:2,

Envelope-to: mykhaylo.dubrovka@saraya.co.in
Delivery-date: Fri, 09 Dec 2022 09:58:51 +0800
Message-ID: <1139606576732.1119371711477.1404958413.0.432054JL.2002@scheduler.constantcontact.com>
Date: Thu, 8 Dec 2022 20:58:00 -0500 (EST)
From: ACROBiosystems <apac@acrobiosystems.com>
Reply-To: apac@acrobiosystems.com
To: mykhaylo.dubrovka@saraya.co.in
Subject: =?utf-8?Q?Key_Biomarkers_for_Alzheimer=E2=80=B2s?=
 =?utf-8?Q?_Disease_and_Parkinson_Disease?=
MIME-Version: 1.0
Content-Type: multipart/alternative; 
	boundary="----=_Part_136016690_1279625916.1670551080951"

------=_Part_136016690_1279625916.1670551080951
Content-Type: text/plain; charset=utf-8
Content-Transfer-Encoding: quoted-printable

Tau&Syn View as Webpage Products Support Resources Insights About Us =E2=80=
=8A Key Biomarkers for Alzheimer=E2=80=B2s Disease and Parkinson Disease Al=
zheimer=E2=80=B2s disease (AD) and Parkinson disease (PD) are two of the mo=
st common neurodegenerative diseases. The diagnosis and treatment of neurod=
egenerative diseases are very difficult. The future research and developmen=
t of related biomarkers may bring hope for these patients. In AD, Tau prote=
in is involved in synaptic plasticity dysfunction caused by A=CE=B2, which =
aggravates memory impairment. Meanwhile, Tau protein can be involved in reg=
ulating the abnormal excitability of A=CE=B2 and Src family tyrosine kinase=
 fyn on neural network, and Tau protein is involved in axon transport dysfu=
nction caused by A=CE=B2. New therapeutic strategies for AD may include blo=
cking the A=CE=B2-induced increase in Tau-dependent NMDA receptor activity =
by reducing fyn levels in dendrites or directly targeting Tau. =E2=80=8A le=
arn more =E2=80=8A learn more Studies reported that =CE=B1-synuclein is the=
 most important protein in the pathogenesis of PD, because it is the main s=
tructural component of Lewy bodies. Many cases of inherited PD are caused b=
y mutations in the gene encoding =CE=B1-synuclein. Although the specific me=
chanism of action remains unclear, =CE=B1-synuclein may become a key biomar=
ker in the diagnosis and treatment of PD. =EF=BC=9E=EF=BC=9EPFFs, A Novel A=
pproach to Modeling Neurodegeneration To receive the latest industry news a=
nd updates from ACROBiosystems, =EF=BB=BFvisit our website & follow us on o=
ur social media!=EF=BB=BF Visit our Website       ACROBiosystems | 1 Innova=
tion Way, Newark, DE 19711 Unsubscribe mykhaylo.dubrovka@saraya.co.in Updat=
e Profile | Our Privacy Policy | Constant Contact Data Notice Sent by apac@=
acrobiosystems.com
------=_Part_136016690_1279625916.1670551080951
Content-Type: text/html; charset=utf-8
Content-Transfer-Encoding: quoted-printable

<!DOCTYPE HTML>
<html lang=3D"en-US"> <head>  <meta http-equiv=3D"Content-Type" content=3D"=
text/html; charset=3Dutf-8"> <meta name=3D"viewport" content=3D"width=3Ddev=
ice-width, initial-scale=3D1, maximum-scale=3D1">   <style type=3D"text/css=
" data-premailer=3D"ignore">=20
@media only screen and (max-width:480px) { .footer-main-width { width: 100%=
 !important; }  .footer-mobile-hidden { display: none !important; }  .foote=
r-mobile-hidden { display: none !important; }  .footer-column { display: bl=
ock !important; }  .footer-mobile-stack { display: block !important; }  .fo=
oter-mobile-stack-padding { padding-top: 3px; } }=20
/* IE: correctly scale images with w/h attbs */ img { -ms-interpolation-mod=
e: bicubic; }=20
.layout { min-width: 100%; }=20
table { table-layout: fixed; } .shell_outer-row { table-layout: auto; }=20
/* Gmail/Web viewport fix */ u + .body .shell_outer-row { width: 620px; }=
=20
/* LIST AND p STYLE OVERRIDES */ .text .text_content-cell p { margin: 0; pa=
dding: 0; margin-bottom: 0; } .text .text_content-cell ul, .text .text_cont=
ent-cell ol { padding: 0; margin: 0 0 0 40px; } .text .text_content-cell li=
 { padding: 0; margin: 0; /* line-height: 1.2; Remove after testing */ } /*=
 Text Link Style Reset */ a { text-decoration: underline; } /* iOS: Autolin=
k styles inherited */ a[x-apple-data-detectors] { text-decoration: underlin=
e !important; font-size: inherit !important; font-family: inherit !importan=
t; font-weight: inherit !important; line-height: inherit !important; color:=
 inherit !important; } /* FF/Chrome: Smooth font rendering */ .text .text_c=
ontent-cell { -webkit-font-smoothing: antialiased; -moz-osx-font-smoothing:=
 grayscale; }=20
</style>   <style>@media only screen and (max-width:480px) {
.button_content-cell {
padding-top: 10px !important; padding-right: 20px !important; padding-botto=
m: 10px !important; padding-left: 20px !important;
}
.button_border-row .button_content-cell {
padding-top: 10px !important; padding-right: 20px !important; padding-botto=
m: 10px !important; padding-left: 20px !important;
}
.column .content-padding-horizontal {
padding-left: 20px !important; padding-right: 20px !important;
}
.layout .column .content-padding-horizontal .content-padding-horizontal {
padding-left: 0px !important; padding-right: 0px !important;
}
.layout .column .content-padding-horizontal .block-wrapper_border-row .cont=
ent-padding-horizontal {
padding-left: 20px !important; padding-right: 20px !important;
}
.dataTable {
overflow: auto !important;
}
.dataTable .dataTable_content {
width: auto !important;
}
.image--mobile-scale .image_container img {
width: auto !important;
}
.image--mobile-center .image_container img {
margin-left: auto !important; margin-right: auto !important;
}
.layout-margin .layout-margin_cell {
padding: 0px 20px !important;
}
.layout-margin--uniform .layout-margin_cell {
padding: 20px 20px !important;
}
.scale {
width: 100% !important; height: auto !important;
}
.stack {
display: block !important; box-sizing: border-box;
}
.hide {
display: none !important;
}
u + .body .shell_outer-row {
width: 100% !important;
}
.socialFollow_container {
text-align: center !important;
}
.text .text_content-cell {
font-size: 16px !important;
}
.text .text_content-cell h1 {
font-size: 24px !important;
}
.text .text_content-cell h2 {
font-size: 20px !important;
}
.text .text_content-cell h3 {
font-size: 20px !important;
}
.text--sectionHeading .text_content-cell {
font-size: 24px !important;
}
.text--heading .text_content-cell {
font-size: 24px !important;
}
.text--dataTable .text_content-cell .dataTable .dataTable_content-cell {
font-size: 14px !important;
}
.text--dataTable .text_content-cell .dataTable th.dataTable_content-cell {
font-size: px !important;
}
}
</style>
</head> <body class=3D"body template template--en-US" data-template-version=
=3D"1.26.0" data-canonical-name=3D"CPE-PT11826" align=3D"center" style=3D"-=
ms-text-size-adjust: 100%; -webkit-text-size-adjust: 100%; min-width: 100%;=
 width: 100%; margin: 0px; padding: 0px;"> <div id=3D"preheader" style=3D"c=
olor: transparent; display: none; font-size: 1px; line-height: 1px; max-hei=
ght: 0px; max-width: 0px; opacity: 0; overflow: hidden;"><span data-entity-=
ref=3D"preheader">Tau&amp;Syn</span></div> <div id=3D"tracking-image" style=
=3D"color: transparent; display: none; font-size: 1px; line-height: 1px; ma=
x-height: 0px; max-width: 0px; opacity: 0; overflow: hidden;"><img src=3D"h=
ttps://r20.rs6.net/on.jsp?ca=3D75cb82c4-bd47-41cb-8b87-8337b28b3780&a=3D111=
9371711477&c=3D16f06cf6-16c7-11ed-a5b0-fa163edfbcfb&ch=3D171040c6-16c7-11ed=
-a5b0-fa163edfbcfb" / alt=3D""></div> <div class=3D"shell" lang=3D"en-US" s=
tyle=3D"background-color: #cccccc;">    <table clas=
s=3D"shell_panel-row" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspa=
cing=3D"0" style=3D"background-image: url('https://imgssl.constantcontact.c=
om/letters/images/PT11826/CityMapBG_BS67894165.png');" background=3D"https:=
//imgssl.constantcontact.com/letters/images/PT11826/CityMapBG_BS67894165.pn=
g"> <tr> <td class=3D"shell_panel-cell" style=3D"" align=3D"center" valign=
=3D"top">  <table class=3D"shell_width-row scale" style=3D"width: 620px;" a=
lign=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td =
class=3D"shell_width-cell" style=3D"padding: 15px 10px;" align=3D"center" v=
align=3D"top">    <table class=3D"shell_content-row" width=3D"100%" align=
=3D"center" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td clas=
s=3D"shell_content-cell" style=3D"background-color: #fefcfc; padding: 0;" a=
lign=3D"center" valign=3D"top" bgcolor=3D"#fefcfc"> <table class=3D"layout =
layout--1-column" style=3D"background-color: #cccccc; table-layout: fixed;"=
 width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" bgcolor=3D=
"#cccccc"> <tr> <td class=3D"column column--1 scale stack" style=3D"width: =
100%;" align=3D"center" valign=3D"top">
<table class=3D"text text--padding-vertical" width=3D"100%" border=3D"0" ce=
llpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td =
class=3D"text_content-cell content-padding-horizontal" style=3D"line-height=
: 1; text-align: left; font-family: Georgia,Times New Roman,Times,serif; co=
lor: #767676; font-size: 14px; display: block; word-wrap: break-word; paddi=
ng: 10px 20px;" align=3D"left" valign=3D"top"><p style=3D"text-align: cente=
r; margin: 0;" align=3D"center"><span style=3D"font-size: 9px; color: rgb(2=
55, 255, 255); font-family: Arial, Verdana, Helvetica, sans-serif;"><A HREF=
=3D"https://r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFG=
titJkwfRZRJ1_NRBBRZ37UhDlWxB58s9GQzIQpw6J_xODUXKlpPa_hyEA1eSiOobRidY_eEwjS_=
7Nm38Jaiuny8XPQr03e5breQTvAeM7Y-n6sYnA=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wI=
Xa1Q3IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9=
V8qAp7cnnswq3S8ZFLg=3D=3D">View as Webpage</A></span></p></td> </tr> </tabl=
e> </td> </tr> </table> <table class=3D"layout layout--1-column" style=3D"t=
able-layout: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspac=
ing=3D"0"> <tr> <td class=3D"column column--1 scale stack" style=3D"width: =
100%;" align=3D"center" valign=3D"top">
<table class=3D"image image--mobile-scale image--mobile-center" width=3D"10=
0%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"ima=
ge_container" align=3D"center" valign=3D"top"> <a href=3D"https://r20.rs6.n=
et/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBOsn4_=
K2EzqNN7rT3dItJW9OXRQpyzhYQXg2GQ-lK13OY8z_iJnFl-W3dTGO3TnjXa8iiTG3_C6YrzBwx=
as5G2Ijj3bOnGVw_hi3JrTBcHHwqujJWU_qRW_LwXJXFYc4Frm3Lk1G_jFRmncS7foGGpb6QOuE=
p9OT7yOMys59GVyWEtPCD0wE_5NP0E_ZGnZVac94REGrVouY-cIhM9u7RCuil0K76cYzH1cvvTX=
lFCmi4fxc5inSiOmknzx1_WcxV-VHHS1q_wnc1AMyGb113INH9XUL_EI_m_Yf6sw5vC2lMu4Xt7=
6qU1E=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D&c=
h=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8ZFLg=3D=3D" data-trac=
kable=3D"true"><img data-image-content class=3D"image_content" width=3D"600=
" src=3D"https://files.constantcontact.com/5f3d0cf9401/d4c83f91-1a31-46c4-a=
72d-8af5752b29ac.jpg" alt=3D"" style=3D"display: block; height: auto; max-w=
idth: 100%;"></a> </td> </tr> </table> </td> </tr> </table> <table class=3D=
"layout layout--navigationBar layout--5-column" style=3D"background-color: =
#cccccc; table-layout: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0=
" cellspacing=3D"0" bgcolor=3D"#cccccc"> <tr> <td class=3D"column column--1=
 scale stack" style=3D"width: 20%;" align=3D"center" valign=3D"middle">
<table class=3D"text text--feature text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"text-align: center; font-family: Georgia,Times New Roman,Times,serif; c=
olor: #2f3131; font-size: 14px; line-height: 1.2; display: block; word-wrap=
: break-word; padding: 10px 0px 10px 20px;" align=3D"center" valign=3D"top"=
><p style=3D"margin: 0;"><a href=3D"https://r20.rs6.net/tn.jsp?f=3D001cb89T=
z0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBDtGqTRbXbNBH4BuOx7EBKyQawnK=
aWBZ8Xm1K_ogzw4-ZeqYp405VyyYzt5cjSw_WCCBFvakGsXF1-8N1J2eCHwXLtoHR67jkyoyBrt=
A8MwGN03ltsuBDvk3JHLQ9n1Kv0SlUlSfSeGswmUWZqLwWS47ODqZiFfgF6eoL_YVr2DaXp2sBP=
y5ZnPBlSz18jY30klU7wmUTNAfrHCHP5R5v064GW1cA9SMTELBMtD7V32l2cMPB6aAIpK9N7Aex=
bN2CKJgPpFCxAZxawftYHocspF3wQ8LTtr1H7Bn3R5F8Udnks45yNgK0948gxwh1mRqKTuvz_aI=
4mgXnX5h6kNUyEd3w2TjKJqB3Q=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCg=
pi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq=
3S8ZFLg=3D=3D" target=3D"_blank" style=3D"font-size: 13px; color: rgb(255, =
255, 255); text-decoration: underline; font-weight: bold; font-family: Aria=
l, Verdana, Helvetica, sans-serif; font-style: normal;">Products</a></p></t=
d> </tr> </table> </td>  <td class=3D"column column--2 scale stack" style=
=3D"width: 20%;" align=3D"center" valign=3D"middle">
<table class=3D"text text--feature text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"text-align: center; font-family: Georgia,Times New Roman,Times,serif; c=
olor: #2f3131; font-size: 14px; line-height: 1.2; display: block; word-wrap=
: break-word; padding: 10px;" align=3D"center" valign=3D"top"><p style=3D"m=
argin: 0;"><a href=3D"https://r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1Tjnjava=
NeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBDtGqTRbXbNBuP3ZixBYwkt5mP_nrF5TiTI2s0CfdW=
eMXKf7pvFSgX-a2mO__NiGuC0m3iVrDsxFWz4UqqoKldwFeRfSLuMhD1wOPXzY3NS0let0oXjQ0=
JeGp8HK1H3I_rDzdXfZvUI1tb9xW1DqMulXPIBEPProml85MA83l7xrK30jtv3fIurqTgz0dWj0=
0sxMFwXfqYkFnzjFPs91E6P-XaAYuxXbxUUDTBROcsvKDpmBYguc7m-OMMM4Zzsb1gbFNl1OfjU=
Y1PEoB2gR4VxNQikNhzvPLw=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7=
LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8=
ZFLg=3D=3D" target=3D"_blank" style=3D"font-size: 13px; color: rgb(255, 255=
, 255); text-decoration: underline; font-family: Arial, Verdana, Helvetica,=
 sans-serif; font-weight: bold; font-style: normal;">Support</a></p></td> <=
/tr> </table> </td>  <td class=3D"column column--3 scale stack" style=3D"wi=
dth: 20%;" align=3D"center" valign=3D"middle">
<table class=3D"text text--feature text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"line-height: 1; text-align: center; font-family: Georgia,Times New Roma=
n,Times,serif; color: #2f3131; font-size: 14px; display: block; word-wrap: =
break-word; padding: 10px;" align=3D"center" valign=3D"top"><p style=3D"mar=
gin: 0;"><a href=3D"https://r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNe=
HvX44PgQTikDznFGtitJkwfRZRJ1_NRBDtGqTRbXbNBgl4jirjLJRbiYa9VvCLpJeRzzekS7uxC=
qhfe5WLChnQtzc2drf3MDliEKrKhdwd8p1_ARcylA0T6ByX49k6WTpXGXam7BSq7iyGRXKg7Su-=
LOYBpg_YZllrVt2X9EwVYMEPV7E8gXiAPhhn-JB36nptzJpTQ9fZZxzWh_Wl30FB7zoW202rAMB=
nEAA90PS4Dbzd_HgC4vECA1V4JHE2Uchq5F1ksDzBPtMSKcv1rowBIYAd9ao_mbcR05CPpVa8F4=
9kRIaLMOY8Abp4O8u4dynIwRSl8pbdC&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgp=
i7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3=
S8ZFLg=3D=3D" target=3D"_blank" style=3D"font-size: 13px; color: rgb(255, 2=
55, 255); text-decoration: underline; font-family: Arial, Verdana, Helvetic=
a, sans-serif; font-weight: bold; font-style: normal;">Resources</a></p></t=
d> </tr> </table> </td>  <td class=3D"column column--4 scale stack" style=
=3D"width: 20%;" align=3D"center" valign=3D"middle">
<table class=3D"text text--feature text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"text-align: center; font-family: Georgia,Times New Roman,Times,serif; c=
olor: #2f3131; font-size: 14px; line-height: 1.2; display: block; word-wrap=
: break-word; padding: 10px;" align=3D"center" valign=3D"top"><p style=3D"m=
argin: 0;"><a href=3D"https://r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1Tjnjava=
NeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBDtGqTRbXbNB0ighq71WO1uMAwXeRp3eaG_HBCrmr2=
SmCn5RXM6ybqqoTNMQczKedGVlyxT3Od7pdPvmQxqr31Q74A8quvykIBp1hdOv1f9IY_BMvSFLK=
nZBJEM0vhU7YVWOqEwa81YRQ8CN0wd2Emb2_1k_2hIXqzuhzP_qUp2M3RNb-9SqQKm8nh-p7Dd5=
FaSF0oZUuAJ0sNd02hkdg9j8Fa_RhQFAz7GjwaEq6bom2msdrtKkrX7NbEt1hcaswGFmSkXlQzb=
LATo4dA_3Jb8=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZf1zOQDmKRQ=
=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8ZFLg=3D=3D" t=
arget=3D"_blank" style=3D"font-size: 13px; color: rgb(255, 255, 255); text-=
decoration: underline; font-family: Arial, Verdana, Helvetica, sans-serif; =
font-weight: bold; font-style: normal;">Insights</a></p></td> </tr> </table=
> </td>  <td class=3D"column column--5 scale stack" style=3D"width: 20%;" a=
lign=3D"center" valign=3D"middle">
<table class=3D"text text--feature text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"text-align: center; font-family: Georgia,Times New Roman,Times,serif; c=
olor: #2f3131; font-size: 14px; line-height: 1.2; display: block; word-wrap=
: break-word; padding: 10px 20px 10px 0px;" align=3D"center" valign=3D"top"=
><p style=3D"margin: 0;"><a href=3D"https://r20.rs6.net/tn.jsp?f=3D001cb89T=
z0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBDtGqTRbXbNBB50j41PG1ac8Hlox=
s7hS-LNtoDhb6UCcyIBr8IcbIY7l_s2QYmXeUEIFJfyaABK11dTxtgzMt4p7NW8YkzZpIyqtEi1=
vd-aJ8IDwzpqxwS_wb9kA4BwJyD04gTvuLnuBho1AnLKBD8NvHqms_QLhivHoGquQ6x8Q67mbQ8=
3p9rsi-QMiOtja7EwZGyjAa--umknhDuiGQqh2F1uSduLz6seR0unp5IpEXD-Fi5--UYWwgtwW1=
8WbTATlvk7gLdZA0Zvp7FyNEAI=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7=
LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8=
ZFLg=3D=3D" target=3D"_blank" style=3D"font-size: 13px; color: rgb(255, 255=
, 255); text-decoration: underline; font-family: Arial, Verdana, Helvetica,=
 sans-serif; font-weight: bold; font-style: normal;">About Us</a></p></td> =
</tr> </table> </td> </tr> </table> <table class=3D"layout layout--1-column=
" style=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cellpadding=3D=
"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 scale stack" styl=
e=3D"width: 100%;" align=3D"center" valign=3D"top"><div class=3D"spacer" st=
yle=3D"line-height: 15px; height: 15px;">&#x200a;</div></td> </tr> </table>=
 <table class=3D"layout layout--feature layout--1-column" style=3D"backgrou=
nd-color: #c03e30; table-layout: fixed;" width=3D"100%" border=3D"0" cellpa=
dding=3D"0" cellspacing=3D"0" bgcolor=3D"#c03e30"> <tr> <td class=3D"column=
 column--1 scale stack" style=3D"width: 100%;" align=3D"center" valign=3D"t=
op">
<table class=3D"text text--feature text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"text-align: center; font-family: Georgia,Times New Roman,Times,serif; c=
olor: #2f3131; font-size: 14px; line-height: 1.2; display: block; word-wrap=
: break-word; padding: 10px 20px;" align=3D"center" valign=3D"top"><p style=
=3D"text-align: center; margin: 0;" align=3D"center"><span style=3D"font-si=
ze: 18px; font-weight: bold; font-family: Arial, Verdana, Helvetica, sans-s=
erif; color: rgb(255, 255, 255);">Key Biomarkers for Alzheimer&#x2032;s Dis=
ease and Parkinson Disease</span></p></td> </tr> </table> </td> </tr> </tab=
le> <table class=3D"layout layout--heading layout--1-column" style=3D"table=
-layout: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=
=3D"0"> <tr> <td class=3D"column column--1 scale stack" style=3D"width: 100=
%;" align=3D"center" valign=3D"top">
<table class=3D"text text--padding-vertical" width=3D"100%" border=3D"0" ce=
llpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td =
class=3D"text_content-cell content-padding-horizontal" style=3D"line-height=
: 1.5; text-align: center; font-family: Georgia,Times New Roman,Times,serif=
; color: #767676; font-size: 14px; display: block; word-wrap: break-word; p=
adding: 10px 20px;" align=3D"center" valign=3D"top"><h1 style=3D"text-align=
: left; font-family: Courier New,Courier,Lucida Sans Typewriter,Lucida Type=
writer,monospace; color: #2f3131; font-size: 20px; font-weight: bold; margi=
n: 0;" align=3D"left">
<span style=3D"font-size: 16px; color: rgb(16, 18, 20); font-family: Arial,=
 Verdana, Helvetica, sans-serif;">A</span><span style=3D"color: rgb(16, 18,=
 20); font-family: Arial, Verdana, Helvetica, sans-serif; font-size: 14px; =
font-weight: normal;">lzheimer&#x2032;s disease (AD) and Parkinson disease =
(PD) are two of the most common neurodegenerative diseases. The diagnosis a=
nd treatment of neurodegenerative diseases are very difficult. The future r=
esearch and development of related biomarkers may bring hope for these pati=
ents.</span>
</h1></td> </tr> </table> </td> </tr> </table> <table class=3D"layout layou=
t--2-column" style=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cel=
lpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1 scale =
stack" style=3D"width: 62.5%;" align=3D"center" valign=3D"top">
<table class=3D"text text--article text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"line-height: 1.5; text-align: left; font-family: Georgia,Times New Roma=
n,Times,serif; color: #2f3131; font-size: 16px; display: block; word-wrap: =
break-word; padding: 10px 10px 10px 20px;" align=3D"left" valign=3D"top"><p=
 style=3D"margin: 0;"><span style=3D"font-family: Arial, Verdana, Helvetica=
, sans-serif; color: rgb(16, 18, 20); font-weight: bold;">I</span><span sty=
le=3D"font-family: Arial, Verdana, Helvetica, sans-serif; color: rgb(16, 18=
, 20); font-size: 14px;">n AD, </span><a href=3D"https://r20.rs6.net/tn.jsp=
?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBMz51gomoek9rQL=
Z503xHrtIi1iSj3vkiO3_Gb7kDhUISAHtZgtjNQOJVd2RwtzQKEIwSTvOzE5NrWayDL7Fl1b7zo=
hQdAC98uvO38AKfLVC6hLK10tCl4-MtROW-5dcX-VlknFZYIE3Z0KoiB_ChTySppzQyoN3uWJq0=
iX-564GtHSyLZ5-pYKmBRpG2ET88nRdEMbgJcodCMSyL76C7DDDApPClTGLkMuhFWEClnSBUcva=
Dzvsz5inNdzcgge-EPQdyPzllc9ydO0j50CHqkE5BLJbVSonhA=3D=3D&c=3D-iUR1FMTROyLgd=
4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO=
9cd-hU4uCAR9V8qAp7cnnswq3S8ZFLg=3D=3D" target=3D"_blank" style=3D"font-fami=
ly: Arial, Verdana, Helvetica, sans-serif; color: rgb(192, 0, 0); font-size=
: 14px; font-weight: normal; text-decoration: underline; font-style: normal=
;">Tau protein</a><span style=3D"font-family: Arial, Verdana, Helvetica, sa=
ns-serif; color: rgb(16, 18, 20); font-size: 14px;"> is involved in synapti=
c plasticity dysfunction caused by A&#x3b2;, which aggravates memory impair=
ment. Meanwhile, Tau protein can be involved in regulating the abnormal exc=
itability of A&#x3b2; and Src family tyrosine kinase fyn on neural network,=
 and Tau protein is involved in axon transport dysfunction caused by A&#x3b=
2;. New therapeutic strategies for AD may include blocking the A&#x3b2;-ind=
uced increase in Tau-dependent NMDA receptor activity by reducing fyn level=
s in dendrites or directly targeting Tau.</span></p></td> </tr> </table> </=
td>  <td class=3D"column column--2 scale stack" style=3D"width: 37.5%;" ali=
gn=3D"center" valign=3D"top">
<div class=3D"spacer" style=3D"height: 30px; line-height: 30px;">&#x200a;</=
div>
<table class=3D"image image--padding-vertical image--mobile-scale image--mo=
bile-center" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0=
"> <tr> <td class=3D"image_container" align=3D"center" valign=3D"top" style=
=3D"padding-top: 10px; padding-bottom: 10px;"> <a href=3D"https://r20.rs6.n=
et/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBMz51g=
omoek9rQLZ503xHrtIi1iSj3vkiO3_Gb7kDhUISAHtZgtjNQOJVd2RwtzQKEIwSTvOzE5NrWayD=
L7Fl1b7zohQdAC98uvO38AKfLVC6hLK10tCl4-MtROW-5dcX-VlknFZYIE3Z0KoiB_ChTySppzQ=
yoN3uWJq0iX-564GtHSyLZ5-pYKmBRpG2ET88nRdEMbgJcodCMSyL76C7DDDApPClTGLkMuhFWE=
ClnSBUcvaDzvsz5inNdzcgge-EPQdyPzllc9ydO0j50CHqkE5BLJbVSonhA=3D=3D&c=3D-iUR1=
FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW=
9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8ZFLg=3D=3D" data-trackable=3D"true"><im=
g data-image-content class=3D"image_content" width=3D"225" src=3D"https://f=
iles.constantcontact.com/5f3d0cf9401/d68a6852-630d-4ed8-8165-db4b9ca0b05f.j=
pg" alt=3D"" style=3D"display: block; height: auto; max-width: 100%;"></a> =
</td> </tr> </table>  <table class=3D"button button--padding-vertical" widt=
h=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-=
layout: fixed;"> <tr> <td class=3D"button_container content-padding-horizon=
tal" align=3D"center" style=3D"padding: 10px 20px 10px 10px;">    <table cl=
ass=3D"button_content-row" style=3D"width: inherit; border-radius: 5px; bor=
der-spacing: 0; background-color: #c03e30; border: none;" border=3D"0" cell=
padding=3D"0" cellspacing=3D"0" bgcolor=3D"#c03e30"> <tr> <td class=3D"butt=
on_content-cell" style=3D"padding: 10px 40px;" align=3D"center"> <a class=
=3D"button_link" href=3D"https://r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1Tjnj=
avaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBMz51gomoek9rQLZ503xHrtIi1iSj3vkiO3_Gb7=
kDhUISAHtZgtjNQOJVd2RwtzQKEIwSTvOzE5NrWayDL7Fl1b7zohQdAC98uvO38AKfLVC6hLK10=
tCl4-MtROW-5dcX-VlknFZYIE3Z0KoiB_ChTySppzQyoN3uWJq0iX-564GtHSyLZ5-pYKmBRpG2=
ET88nRdEMbgJcodCMSyL76C7DDDApPClTGLkMuhFWEClnSBUcvaDzvsz5inNdzcgge-EPQdyPzl=
lc9ydO0j50CHqkE5BLJbVSonhA=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCg=
pi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq=
3S8ZFLg=3D=3D" data-trackable=3D"true" style=3D"color: #FFFFFF; font-family=
: Arial,Verdana,Helvetica,sans-serif; font-size: 10px; word-wrap: break-wor=
d; font-weight: bold; text-decoration: none;">learn more</a> </td> </tr> </=
table>    </td> </tr> </table>   </td> </tr> </table> <table class=3D"layou=
t layout--2-column" style=3D"table-layout: fixed;" width=3D"100%" border=3D=
"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"column column--1=
 scale stack" style=3D"width: 42.5%;" align=3D"center" valign=3D"top">
<div class=3D"spacer" style=3D"height: 30px; line-height: 30px;">&#x200a;</=
div>
<table class=3D"image image--padding-vertical image--mobile-scale image--mo=
bile-center" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0=
"> <tr> <td class=3D"image_container content-padding-horizontal" align=3D"c=
enter" valign=3D"top" style=3D"padding: 10px 10px 10px 20px;"> <a href=3D"h=
ttps://r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJk=
wfRZRJ1_NRBBHHpF1bAeZJzwCmisYhEK69YGNkX2wJKRz0yTVdz2ZmAE9qFTFEOS7SbVXDrW-6O=
CXfvby-es-pTDn_v7-12LrJ1-MJd29Cod674Sh7JjfPubEV3usYPkp1-hLWBwpPe8sLtYm9HgtW=
gliIdXR-y4npqT9bZEvq9rwx_hgxZLQ8I6ZAu1mdMSLA-J9aijiCesn80s14F6UTgsouv6bopR4=
aAPKy5WyjMZnD4rioYAXfEolOfI5QLbYNqU0Q2CR6JF4vVsHX7dftjWWjhwXVzsnYIH_qbz8lGc=
LWduXvgkzk&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D=
&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8ZFLg=3D=3D" data-tr=
ackable=3D"true"><img data-image-content class=3D"image_content" width=3D"2=
25" src=3D"https://files.constantcontact.com/5f3d0cf9401/d942d691-383c-42f5=
-a9f9-1f2ac34c5b0f.jpg" alt=3D"" style=3D"display: block; height: auto; max=
-width: 100%;"></a> </td> </tr> </table>  <table class=3D"button button--pa=
dding-vertical" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=
=3D"0" style=3D"table-layout: fixed;"> <tr> <td class=3D"button_container c=
ontent-padding-horizontal" align=3D"center" style=3D"padding: 10px 10px 10p=
x 20px;">    <table class=3D"button_content-row" style=3D"width: inherit; b=
order-radius: 5px; border-spacing: 0; background-color: #c03e30; border: no=
ne;" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" bgcolor=3D"#c03e30"> =
<tr> <td class=3D"button_content-cell" style=3D"padding: 10px 40px;" align=
=3D"center"> <a class=3D"button_link" href=3D"https://r20.rs6.net/tn.jsp?f=
=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBBHHpF1bAeZJzwCmi=
sYhEK69YGNkX2wJKRz0yTVdz2ZmAE9qFTFEOS7SbVXDrW-6OCXfvby-es-pTDn_v7-12LrJ1-MJ=
d29Cod674Sh7JjfPubEV3usYPkp1-hLWBwpPe8sLtYm9HgtWgliIdXR-y4npqT9bZEvq9rwx_hg=
xZLQ8I6ZAu1mdMSLA-J9aijiCesn80s14F6UTgsouv6bopR4aAPKy5WyjMZnD4rioYAXfEolOfI=
5QLbYNqU0Q2CR6JF4vVsHX7dftjWWjhwXVzsnYIH_qbz8lGcLWduXvgkzk&c=3D-iUR1FMTROyL=
gd4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzM=
LO9cd-hU4uCAR9V8qAp7cnnswq3S8ZFLg=3D=3D" data-trackable=3D"true" style=3D"c=
olor: #FFFFFF; font-family: Arial,Verdana,Helvetica,sans-serif; font-size: =
10px; word-wrap: break-word; font-weight: bold; text-decoration: none;">lea=
rn more</a> </td> </tr> </table>    </td> </tr> </table>   </td>  <td class=
=3D"column column--2 scale stack" style=3D"width: 57.5%;" align=3D"center" =
valign=3D"top">
<table class=3D"text text--article text--padding-vertical" width=3D"100%" b=
order=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixe=
d;"> <tr> <td class=3D"text_content-cell content-padding-horizontal" style=
=3D"line-height: 1.5; text-align: left; font-family: Georgia,Times New Roma=
n,Times,serif; color: #2f3131; font-size: 16px; display: block; word-wrap: =
break-word; padding: 10px 20px 10px 10px;" align=3D"left" valign=3D"top"><p=
 style=3D"margin: 0;"><span style=3D"font-family: Arial, Verdana, Helvetica=
, sans-serif; color: rgb(16, 18, 20); font-weight: bold;">S</span><span sty=
le=3D"font-family: Arial, Verdana, Helvetica, sans-serif; color: rgb(16, 18=
, 20); font-size: 14px;">tudies reported that </span><a href=3D"https://r20=
.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NR=
BBHHpF1bAeZJzwCmisYhEK69YGNkX2wJKRz0yTVdz2ZmAE9qFTFEOS7SbVXDrW-6OCXfvby-es-=
pTDn_v7-12LrJ1-MJd29Cod674Sh7JjfPubEV3usYPkp1-hLWBwpPe8sLtYm9HgtWgliIdXR-y4=
npqT9bZEvq9rwx_hgxZLQ8I6ZAu1mdMSLA-J9aijiCesn80s14F6UTgsouv6bopR4aAPKy5WyjM=
ZnD4rioYAXfEolOfI5QLbYNqU0Q2CR6JF4vVsHX7dftjWWjhwXVzsnYIH_qbz8lGcLWduXvgkzk=
&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev=
_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8ZFLg=3D=3D" target=3D"_blank"=
 style=3D"font-family: Arial, Verdana, Helvetica, sans-serif; color: rgb(19=
2, 0, 0); font-size: 14px; font-weight: normal; text-decoration: underline;=
 font-style: normal;">&#x3b1;-synuclein</a><span style=3D"font-family: Aria=
l, Verdana, Helvetica, sans-serif; color: rgb(16, 18, 20); font-size: 14px;=
"> is the most important protein in the pathogenesis of PD, because it is t=
he main structural component of Lewy bodies. Many cases of inherited PD are=
 caused by mutations in the gene encoding &#x3b1;-synuclein. Although the s=
pecific mechanism of action remains unclear, &#x3b1;-synuclein may become a=
 key biomarker in the diagnosis </span><span style=3D"font-family: Arial, V=
erdana, Helvetica, sans-serif; font-size: 14px;">and treatment </span><span=
 style=3D"font-family: Arial, Verdana, Helvetica, sans-serif; color: rgb(16=
, 18, 20); font-size: 14px;">of PD.</span></p></td> </tr> </table> </td> </=
tr> </table> <table class=3D"layout layout--heading layout--1-column" style=
=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" cel=
lspacing=3D"0"> <tr> <td class=3D"column column--1 scale stack" style=3D"wi=
dth: 100%;" align=3D"center" valign=3D"top">
<table class=3D"text text--padding-vertical" width=3D"100%" border=3D"0" ce=
llpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td =
class=3D"text_content-cell content-padding-horizontal" style=3D"text-align:=
 center; font-family: Georgia,Times New Roman,Times,serif; color: #767676; =
font-size: 14px; line-height: 1.2; display: block; word-wrap: break-word; p=
adding: 10px 20px;" align=3D"center" valign=3D"top"><h1 style=3D"font-famil=
y: Courier New,Courier,Lucida Sans Typewriter,Lucida Typewriter,monospace; =
color: #2f3131; font-size: 20px; font-weight: bold; margin: 0;"><a href=3D"=
https://r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJ=
kwfRZRJ1_NRBD4qYoBVz68kenwhzNIEeiQRrbABoJQNdi5PyEZMiWF35T47Qi8KkumVOiSdHzGC=
T_3hD3GXw8uUzem-60QeCEidANnafO6LOWHQ1B578vQnHWXyqrn4BFu0bCVpgoN1HPDH_ANMGfB=
Dmm-SnDgfsSfvHuClpECjMWVX181sOxcgJmSznJ69IMfzfA4ZhzLkHpRYPUEAqjOSd_K4zJb5kF=
VJGhehBQ8PgL9tXSUdB_wBoUfDz0g1aGWCb4IkoklTyAgxTh-KKR9pc2M-WLcwkS0Au8d0eMKOg=
KTLv3eRMe17mCQYALLNrDCB1-rlrkQjBg=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3=
IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp=
7cnnswq3S8ZFLg=3D=3D" target=3D"_blank" style=3D"font-weight: normal; color=
: rgb(192, 0, 0); font-family: Arial, Verdana, Helvetica, sans-serif; font-=
size: 14px; text-decoration: underline; font-style: normal;">&#xff1e;&#xff1=
e;PFFs, A Novel Approach to Modeling Neurodegeneration</a></h1></td> </tr> =
</table> </td> </tr> </table> <table class=3D"layout layout--1-column" styl=
e=3D"table-layout: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" ce=
llspacing=3D"0"> <tr> <td class=3D"column column--1 scale stack" style=3D"w=
idth: 100%;" align=3D"center" valign=3D"top">
<table class=3D"image image--padding-vertical image--mobile-scale image--mo=
bile-center" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0=
"> <tr> <td class=3D"image_container content-padding-horizontal" align=3D"c=
enter" valign=3D"top" style=3D"padding: 10px 20px;"> <a href=3D"https://r20=
.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NR=
BD4qYoBVz68kenwhzNIEeiQRrbABoJQNdi5PyEZMiWF35T47Qi8KkumVOiSdHzGCT_3hD3GXw8u=
Uzem-60QeCEidANnafO6LOWHQ1B578vQnHWXyqrn4BFu0bCVpgoN1HPDH_ANMGfBDmm-SnDgfsS=
fvHuClpECjMWVX181sOxcgJmSznJ69IMfzfA4ZhzLkHpRYPUEAqjOSd_K4zJb5kFVJGhehBQ8Pg=
L9tXSUdB_wBoUfDz0g1aGWCb4IkoklTyAgxTh-KKR9pc2M-WLcwkS0Au8d0eMKOgKTLv3eRMe17=
mCQYALLNrDCB1-rlrkQjBg=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7L=
HZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8Z=
FLg=3D=3D" data-trackable=3D"true"><img data-image-content class=3D"image_c=
ontent" width=3D"513" src=3D"https://files.constantcontact.com/5f3d0cf9401/=
e01ffba8-fefb-4d0b-ba21-a0dc8787c4c1.jpg" alt=3D"" style=3D"display: block;=
 height: auto; max-width: 100%;"></a> </td> </tr> </table> </td> </tr> </ta=
ble> <table class=3D"layout layout--1-column" style=3D"table-layout: fixed;=
" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"> <tr> <td=
 class=3D"column column--1 scale stack" style=3D"width: 100%;" align=3D"cen=
ter" valign=3D"top">
<table class=3D"divider divider--dashed" width=3D"100%" cellpadding=3D"0" c=
ellspacing=3D"0" border=3D"0"> <tr> <td class=3D"divider_container content-=
padding-horizontal" style=3D"padding: 10px 20px;" width=3D"100%" align=3D"c=
enter" valign=3D"top"> <table class=3D"divider_content-row" style=3D"height=
: 1px; width: 100%;" cellpadding=3D"0" cellspacing=3D"0" border=3D"0"> <tr>=
 <td class=3D"divider_content-cell" style=3D"height: 1px; line-height: 1px;=
 padding-bottom: 0px; background-color: transparent; border-bottom-width: 1=
px; border-bottom-style: dashed; border-bottom-color: #555556;" height=3D"1=
" align=3D"center" bgcolor=3D"transparent"> <img alt=3D"" width=3D"5" heigh=
t=3D"1" border=3D"0" hspace=3D"0" vspace=3D"0" src=3D"https://imgssl.consta=
ntcontact.com/letters/images/1101116784221/S.gif" style=3D"display: block; =
height: 1px; width: 5px;"> </td> </tr> </table> </td> </tr> </table> </td> =
</tr> </table> <table class=3D"layout layout--1-column" style=3D"table-layo=
ut: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0"=
> <tr> <td class=3D"column column--1 scale stack" style=3D"width: 100%;" al=
ign=3D"center" valign=3D"top">
<table class=3D"image image--padding-vertical image--mobile-scale image--mo=
bile-center" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0=
"> <tr> <td class=3D"image_container content-padding-horizontal" align=3D"c=
enter" valign=3D"top" style=3D"padding: 10px 20px;"> <a href=3D"https://r20=
.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NR=
BHaha3UahWJcRDMXhlCUZ7yzonPgD6n_D_M5ENq8KK4EvR6du0jEzobrIfCKTbRhXQaEZb4Tcaz=
0UGPSWNI4JEAbkPl4qq9Wy1wDdyo_lX9Q40MyAb-nkYH6oHw4yvyMzdGiIC5wYCmsv48nKA6t0G=
ngXsPKr-IviVPDGCAr_5cSDOKQrk0Tct8t75zSVmUzwlaE7-I-pXSjO-4LAcDOF41FuHHSh-wSX=
PSHEI8TntkQvkPPBPep2Wvp1JF48p-HsQ=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3=
IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp=
7cnnswq3S8ZFLg=3D=3D" data-trackable=3D"true"><img data-image-content class=
=3D"image_content" width=3D"500" src=3D"https://files.constantcontact.com/5=
f3d0cf9401/05f67830-0d5a-439e-83fe-f46a710d4dcf.png" alt=3D"" style=3D"disp=
lay: block; height: auto; max-width: 100%;"></a> </td> </tr> </table> </td>=
 </tr> </table> <table class=3D"layout layout--1-column" style=3D"table-lay=
out: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0=
"> <tr> <td class=3D"column column--1 scale stack" style=3D"width: 100%;" a=
lign=3D"center" valign=3D"top">
<table class=3D"text text--padding-vertical" width=3D"100%" border=3D"0" ce=
llpadding=3D"0" cellspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td =
class=3D"text_content-cell content-padding-horizontal" style=3D"line-height=
: 1.2; text-align: left; font-family: Georgia,Times New Roman,Times,serif; =
color: #767676; font-size: 14px; display: block; word-wrap: break-word; pad=
ding: 10px 20px;" align=3D"left" valign=3D"top">
<p style=3D"text-align: center; margin: 0;" align=3D"center"><span style=3D=
"color: rgb(76, 76, 76); font-family: Arial, Verdana, Helvetica, sans-serif=
;">To receive the latest industry news and updates from ACROBiosystems, </s=
pan></p>
<p style=3D"text-align: center; margin: 0;" align=3D"center"><span style=3D=
"color: rgb(76, 76, 76); font-weight: bold; font-family: Arial, Verdana, He=
lvetica, sans-serif;">&#xfeff;visit our website &amp; follow us on our soci=
al media!&#xfeff;</span></p>
</td> </tr> </table> </td> </tr> </table> <table class=3D"layout layout--se=
ctionHeading layout--2-column" style=3D"table-layout: fixed; background-col=
or: #2f3131;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"=
0" bgcolor=3D"#2f3131"> <tr> <td class=3D"column column--1 scale stack" sty=
le=3D"width: 50%;" align=3D"center" valign=3D"top"> <table class=3D"button =
button--padding-vertical" width=3D"100%" border=3D"0" cellpadding=3D"0" cel=
lspacing=3D"0" style=3D"table-layout: fixed;"> <tr> <td class=3D"button_con=
tainer content-padding-horizontal" align=3D"left" style=3D"padding: 10px 10=
px 10px 20px;">    <table class=3D"button_content-row" style=3D"border-radi=
us: 5px; width: inherit; border-spacing: 0; background-color: #c03e30; bord=
er: none;" border=3D"0" cellpadding=3D"0" cellspacing=3D"0" bgcolor=3D"#c03=
e30"> <tr> <td class=3D"button_content-cell" style=3D"padding: 10px 40px;" =
align=3D"center"> <a class=3D"button_link" href=3D"https://r20.rs6.net/tn.j=
sp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBHaha3UahWJcR=
DMXhlCUZ7yzonPgD6n_D_M5ENq8KK4EvR6du0jEzobrIfCKTbRhXQaEZb4Tcaz0UGPSWNI4JEAb=
kPl4qq9Wy1wDdyo_lX9Q40MyAb-nkYH6oHw4yvyMzdGiIC5wYCmsv48nKA6t0GngXsPKr-IviVP=
DGCAr_5cSDOKQrk0Tct8t75zSVmUzwlaE7-I-pXSjO-4LAcDOF41FuHHSh-wSXPSHEI8TntkQvk=
PPBPep2Wvp1JF48p-HsQ=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZ=
f1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8ZFL=
g=3D=3D" data-trackable=3D"true" style=3D"font-family: Arial,Verdana,Helvet=
ica,sans-serif; color: #FFFFFF; font-size: 10px; word-wrap: break-word; fon=
t-weight: bold; text-decoration: none;">Visit our Website</a> </td> </tr> <=
/table>    </td> </tr> </table>   </td>  <td class=3D"column column--2 scal=
e stack" style=3D"width: 50%;" align=3D"center" valign=3D"top">
<table class=3D"socialFollow socialFollow--padding-vertical" width=3D"100%"=
 cellpadding=3D"0" cellspacing=3D"0" border=3D"0"> <tr> <td class=3D"social=
Follow_container content-padding-horizontal" width=3D"100%" align=3D"right"=
 valign=3D"top" style=3D"height: 1px; line-height: 1px; padding: 10px 20px =
10px 10px;"> <a href=3D"https://r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1Tjnja=
vaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBJELcQB7LmPfinMrQU-Q1HaoSW1GsQwX94m81vcI=
WYlWZekgORC_FinhWwV8HzaUI-fiMS5YE2oP_k9PjgU6oGaINNW7tc-4j2VGwn6hv2kxBQ2pCh4=
I6tSYjWS-upJ59Xv9nLqjrh1wBcOm1KYvaSzkUrpCFTNddWGdHKEAskrevAK81DQXce_vtcHPMT=
uKRhJqJP1v0HxezsO2Btdjzfq679E6eeHSlA9rIbiBcq3Gmtzv0N66O65m8iiqRL6eQzHOYBH4T=
CWfPa8evZ0b0gQ=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZf1zOQDmKR=
Q=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8ZFLg=3D=3D" =
data-trackable=3D"true"><img class=3D"socialFollow_icon" alt=3D"Facebook" w=
idth=3D"32" border=3D"0" src=3D"https://imgssl.constantcontact.com/letters/=
images/CPE/SocialIcons/circles/circleColor_Facebook.png" style=3D"display: =
inline-block; margin: 0; padding: 0;"></a> &#xa0;<a href=3D"https://r20.rs6=
.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ1_NRBNl2=
GrOALIsTgsz8KpR3x0OvrmFjZ8wP2r3RTMi-gG4dRlydpYCE_fPwOqeEDYi6lOj_8dAb2Cv80U7=
sFLSf0pBnGSvgdW-Mr9p2oIA2bYmw1EygJHeKhhjNsvpKqrEF-zX_dXyzM1siRsGjsPNgVtv6kH=
y7RlORh69pUf2ZVMhQlicuNtasT0CSHpqQB6-fE6AJJQ_88_6IcoD6tIYytQ8RSqPElUFBBsDFH=
zna5_KEGSBPO5EzrMzD9RdJvZpkr1lW54X-94C4_dyXuNGceriIl9dr-6-mzHdeBz6AIvXk1WPY=
BAfbcKJbztM8wUn33Q=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3IIPcoCgpi7LHZf1=
zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7cnnswq3S8ZFLg=
=3D=3D" data-trackable=3D"true"><img class=3D"socialFollow_icon" alt=3D"Lin=
kedIn" width=3D"32" border=3D"0" src=3D"https://imgssl.constantcontact.com/=
letters/images/CPE/SocialIcons/circles/circleColor_LinkedIn.png" style=3D"d=
isplay: inline-block; margin: 0; padding: 0;"></a> &#xa0;<a href=3D"https:/=
/r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFGtitJkwfRZRJ=
1_NRBJfLomAMwLLAHX_JH4C1sdK1Pw0M7aoTzi2KGku69M3qVmlLKbflJpDz7hd3gF0al27pISI=
V76On7gZm8MOHnahUTtjh2oM_hKjc1TYqD_wU&c=3D-iUR1FMTROyLgd4aY4qlHb__wIXa1Q3II=
PcoCgpi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V8qAp7c=
nnswq3S8ZFLg=3D=3D" data-trackable=3D"true"><img class=3D"socialFollow_icon=
" alt=3D"Twitter" width=3D"32" border=3D"0" src=3D"https://imgssl.constantc=
ontact.com/letters/images/CPE/SocialIcons/circles/circleColor_Twitter.png" =
style=3D"display: inline-block; margin: 0; padding: 0;"></a> &#xa0;<a href=
=3D"https://r20.rs6.net/tn.jsp?f=3D001cb89Tz0hpJy1TjnjavaNeHvX44PgQTikDznFG=
titJkwfRZRJ1_NRBG4pbRqNRWeohgmnGbb2yXVlRiiAI1yoMP0Kdw8TbvsYSIA5mXw_CUPELNHo=
kgAsFoJolcjDwPOaQolazE3-q_lxHxwER9RBMqb-ToENQZ2HBim4xjVWJcFtfPQXEkUsHw9iSbJ=
4s1gkwHF05foPN9D_XxQlEawlFjxRCRc7J8atVgyDBEumbwk7q88LrhT6SdznOMsWIrDxec9ryK=
Tlj9gDgTjXM_49O-3dh4YXpf5_5JGQkYIPPliiTN5naUQSOyZ3iT34lBfI4m93NCStd5x469IwF=
PUxB1qy1e3OH6Mym10w1lS4xWyl9RTCr1r9Ag=3D=3D&c=3D-iUR1FMTROyLgd4aY4qlHb__wIX=
a1Q3IIPcoCgpi7LHZf1zOQDmKRQ=3D=3D&ch=3Druev_cTh1u--cW9Kn9LzMLO9cd-hU4uCAR9V=
8qAp7cnnswq3S8ZFLg=3D=3D" data-trackable=3D"true"><img class=3D"socialFollo=
w_icon" alt=3D"YouTube" width=3D"32" border=3D"0" src=3D"https://imgssl.con=
stantcontact.com/letters/images/CPE/SocialIcons/circles/circleColor_YouTube=
.png" style=3D"display: inline-block; margin: 0; padding: 0;"></a> </td> </=
tr> </table> </td> </tr> </table>  </td> </tr> </table>    </td> </tr> </ta=
ble>  </td> </tr> <tr> <td class=3D"shell_panel-cell shell_panel-cell--syst=
emFooter" style=3D"" align=3D"center" valign=3D"top">  <table class=3D"shel=
l_width-row scale" style=3D"width: 100%;" align=3D"center" border=3D"0" cel=
lpadding=3D"0" cellspacing=3D"0"> <tr> <td class=3D"shell_width-cell" style=
=3D"padding: 0px;" align=3D"center" valign=3D"top">    <table class=3D"shel=
l_content-row" width=3D"100%" align=3D"center" border=3D"0" cellpadding=3D"=
0" cellspacing=3D"0"> <tr> <td class=3D"shell_content-cell" style=3D"backgr=
ound-color: #fefcfc; padding: 0;" align=3D"center" valign=3D"top" bgcolor=
=3D"#fefcfc"> <table class=3D"layout layout--1-column" style=3D"table-layou=
t: fixed;" width=3D"100%" border=3D"0" cellpadding=3D"0" cellspacing=3D"0">=
 <tr> <td class=3D"column column--1 scale stack" style=3D"width: 100%;" ali=
gn=3D"center" valign=3D"top"> <table class=3D"footer" width=3D"100%" border=
=3D"0" cellpadding=3D"0" cellspacing=3D"0" style=3D"font-family: Verdana,Ge=
neva,sans-serif; color: #5d5d5d; font-size: 12px;"> <tr> <td class=3D"foote=
r_container" align=3D"center"> <table class=3D"footer-container" width=3D"1=
00%" cellpadding=3D"0" cellspacing=3D"0" border=3D"0" style=3D"background-c=
olor: #ffffff; margin-left: auto; margin-right: auto; table-layout: auto !i=
mportant;" bgcolor=3D"#ffffff">
<tr>
<td width=3D"100%" align=3D"center" valign=3D"top" style=3D"width: 100%;">
<div class=3D"footer-max-main-width" align=3D"center" style=3D"margin-left:=
 auto; margin-right: auto; max-width: 100%;">
<table width=3D"100%" cellpadding=3D"0" cellspacing=3D"0" border=3D"0">
<tr>
<td class=3D"footer-layout" align=3D"center" valign=3D"top" style=3D"paddin=
g: 16px 0px;">
<table class=3D"footer-main-width" style=3D"width: 580px;" border=3D"0" cel=
lpadding=3D"0" cellspacing=3D"0">
<tr>
<td class=3D"footer-text" align=3D"center" valign=3D"top" style=3D"color: #=
5d5d5d; font-family: Verdana,Geneva,sans-serif; font-size: 12px; padding: 4=
px 0px;">
<span class=3D"footer-column">ACROBiosystems<span class=3D"footer-mobile-hi=
dden"> | </span></span><span class=3D"footer-column">1 Innovation Way<span =
class=3D"footer-mobile-hidden">, </span></span><span class=3D"footer-column=
"></span><span class=3D"footer-column"></span><span class=3D"footer-column"=
>Newark, DE 19711</span><span class=3D"footer-column"></span>
</td>
</tr>
<tr>
<td class=3D"footer-row" align=3D"center" valign=3D"top" style=3D"padding: =
10px 0px;">
<table cellpadding=3D"0" cellspacing=3D"0" border=3D"0">
<tr>
<td class=3D"footer-text" align=3D"center" valign=3D"top" style=3D"color: #=
5d5d5d; font-family: Verdana,Geneva,sans-serif; font-size: 12px; padding: 4=
px 0px;">
<a href=3D"https://visitor.constantcontact.com/do?p=3Dun&m=3D0019H8nW6INX1K=
tRUXbJ_ZGYQ%3D&ch=3D171040c6-16c7-11ed-a5b0-fa163edfbcfb&ca=3D75cb82c4-bd47=
-41cb-8b87-8337b28b3780" data-track=3D"false" style=3D"color: #5d5d5d;">Uns=
ubscribe mykhaylo.dubrovka@saraya.co.in<span class=3D"partnerOptOut"></span=
></a>
<span class=3D"partnerOptOut"></span>
</td>
</tr>
<tr>
<td class=3D"footer-text" align=3D"center" valign=3D"top" style=3D"color: #=
5d5d5d; font-family: Verdana,Geneva,sans-serif; font-size: 12px; padding: 4=
px 0px;">
<a href=3D"https://visitor.constantcontact.com/do?p=3Doo&m=3D0019H8nW6INX1K=
tRUXbJ_ZGYQ%3D&ch=3D171040c6-16c7-11ed-a5b0-fa163edfbcfb&ca=3D75cb82c4-bd47=
-41cb-8b87-8337b28b3780" data-track=3D"false" style=3D"color: #5d5d5d;">Upd=
ate Profile</a> |
<a href=3D"https://www.acrobiosystems.com/A49-AcroBiosystems-Privacy-Policy=
.html" data-track=3D"false" style=3D"color: #5d5d5d;">Our Privacy Policy</a=
><span class=3D"footer-mobile-hidden"> |</span>
<a class=3D"footer-about-provider footer-mobile-stack footer-mobile-stack-p=
adding" href=3D"http://www.constantcontact.com/legal/about-constant-contact=
" data-track=3D"false" style=3D"color: #5d5d5d;">Constant Contact Data Noti=
ce</a>
</td>
</tr>
<tr>
<td class=3D"footer-text" align=3D"center" valign=3D"top" style=3D"color: #=
5d5d5d; font-family: Verdana,Geneva,sans-serif; font-size: 12px; padding: 4=
px 0px;">
Sent by
<a href=3D"mailto:apac@acrobiosystems.com" style=3D"color: #5d5d5d; text-de=
coration: none;">apac@acrobiosystems.com</a>
</td>
</tr>
</table>
</td>
</tr>
<tr>
<td class=3D"footer-text" align=3D"center" valign=3D"top" style=3D"color: #=
5d5d5d; font-family: Verdana,Geneva,sans-serif; font-size: 12px; padding: 4=
px 0px;">
</td>
</tr>
</table>
</td>
</tr>
</table>
</div>
</td>
</tr>
</table> </td> </tr> </table>   </td> </tr> </table>  </td> </tr> </table> =
   </td> </tr> </table>  </td> </tr>  </table> </div>  </body> </html>

------=_Part_136016690_1279625916.1670551080951--