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Subject: =?utf-8?Q?Reminder=3A=20Reliable=20Antifungal=20Susceptibility=20Testing=20with=20MICRONAUT=2DAM=20according=20to=20EUCAST=20standards?=
From: =?utf-8?Q?Labroots=20for=20Bruker=20Microbiology=20&=20Diagnostics?= <info@labroots.com>
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Date: Wed, 28 Sep 2022 10:29:53 +0000
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Free Webinar - Register Today!

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hly-multiplexed-and-multi-modal-spatial-omics-chipcytometry-datasets-22489=
4?e=3D75d21e8f3b)
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** Reliable Antifungal Susceptibility Testing with MICRONAUT-AM according=
 to EUCAST standards
------------------------------------------------------------

September 29=2C 2022
https://www.labroots.com/intercall/add-to-calendar/Webinar/7586?start-date=
=3D20220929T060000&end-date=3D20220929T070000&TZID=3DAmerica/Los_Angeles6:=
00am (PDT)=2C  9:00am (EDT)=2C
3:00pm (CEST)
Presented by:
https://www.labroots.com/ms/webinar/reliable-antifungal-susceptibility-tes=
ting-micronaut-am-according-eucast-standards?campaign=3Dlremail
Alix Coste=2C PhD=2C FAMH
Clinical microbiologist=2C
University hospital Lausanne

=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=
=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=
=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D=3D
The global burden of candidiasis remains relatively stable. However=2C the=
 epidemiology of the last ten years shows a shift from a majority of Candi=
da albicans infections to non-albicans species. Species such as C. glabrat=
a=2C C. parapsilosis or C. tropicalis=2C not to mention C. auris=2C are in=
creasingly reported and are among the most prevalent species in some count=
ries. These species are known to be naturally less sensitive to antifungal=
 drugs or to rapidly acquire resistance. Therefore=2C reliable antifungal=
 susceptibility testing (AFST) is essential to address the threat of antif=
ungal resistance and improve patient outcomes.

CLSI and EUCAST offer different AFST protocols and interpretive criteria f=
or detecting antifungal resistance or at least decreased antifungal suscep=
tibility. However=2C both reference methods are labor intensive=2C making=
 them difficult to implement in a routine laboratory. In contrast=2C comme=
rcial broth microdilution (BMD) methods offer a simpler and easier-to-impl=
ement alternative. MICRONAUT-AM (Bruker Daltonics GmbH & Co. KG.) is a BMD=
 solution based on the EUCAST protocol and interpreted according to EUCAST=
 criteria=2C whereas Sensititre=E2=84=A2 YeastOne=E2=84=A2 (Thermo Fisher=
 Scientific) follows the CLSI protocol and interpretations=2C making it di=
fficult to compare the results of both products. To overcome the differenc=
es between EUCAST and CLSI=2C a comparative evaluation of the MICRONAUT-AM=
 test system using antifungal resistance genes was performed at CHUV Lausa=
nne=2C Switzerland. The results=2C findings and conclusions of the study w=
ill be presented in this webinar by Dr. Alix Coste=2C PhD=2C Clinical
Microbiologist=2C expert in mycology.

Learning Objectives
* Understand the difference between CLSI and EUCAST AFST
* Identify the benefits of MICRONAUT-AM
* Learn about the performance of MICRONAUT-AM

Please contact your local representative for availability in your country.=
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00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
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t-text-size-adjust: 100%;">
              =09
=09=09=09
=09=09=09=09
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;" width=3D"100%" class=3D"mcnTextContent=
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<h1 style=3D"display: block;margin: 0;padding:=
 0;color: #333333;font-family: Helvetica;font-size: 24px;font-style: norma=
l;font-weight: normal;line-height: 125%;letter-spacing: normal;text-align:=
 left;"><span style=3D"font-size:26px">Reliable Antifungal Susceptibility=
 Testing with MICRONAUT-AM according to EUCAST standards</span></h1>

<p style=3D"line-height: 125%;text-align: left;margin: 10px 0;padding: 0;m=
so-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-=
adjust: 100%;color: #202020;font-family: Helvetica;font-size: 14px;"><span=
 style=3D"color:#00497E"><strong>September 29=2C 2022</strong></span><br>
<a href=3D"https://labroots.us7.list-manage.com/track/click?u=3D6f39393ef3=
8fb324428ff8c2c&id=3D2e241d030a&e=3D75d21e8f3b" target=3D"_blank" style=
=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webkit-text-=
size-adjust: 100%;color: #1e8ae7;font-weight: normal;text-decoration: unde=
rline;"><img data-file-id=3D"42943" height=3D"13" src=3D"https://gallery.m=
ailchimp.com/6f39393ef38fb324428ff8c2c/images/b9d0b3b5-66ac-4b86-857f-08e5=
d0e67a46.png" style=3D"border: 0px;width: 20px;height: 13px;margin: 0px;ou=
tline: none;text-decoration: none;-ms-interpolation-mode: bicubic;" width=
=3D"20"></a>6:00am (PDT)=2C&nbsp; 9:00am (EDT)=2C<br>
&nbsp; &nbsp; &nbsp;3:00pm (CEST)</p>

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=09=09=09=09

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lpadding=3D"0" cellspacing=3D"0" width=3D"300" class=3D"columnWrapper" sty=
le=3D"border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rspace: 0p=
t;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
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lumnContainer" style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust=
: 100%;-webkit-text-size-adjust: 100%;"><table border=3D"0" cellpadding=3D=
"0" cellspacing=3D"0" width=3D"100%" class=3D"mcnTextBlock" style=3D"min-w=
idth: 100%;border-collapse: collapse;mso-table-lspace: 0pt;mso-table-rspac=
e: 0pt;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;">
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g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
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pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;" width=3D"100%" class=3D"mcnTextContent=
Container">
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<strong>Presented by:</strong>
                        </td>
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=09=09=09=09

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</table><table border=3D"0" cellpadding=3D"0" cellspacing=3D"0" width=3D"1=
00%" class=3D"mcnTextBlock" style=3D"min-width: 100%;border-collapse: coll=
apse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 100=
%;-webkit-text-size-adjust: 100%;">
    <tbody class=3D"mcnTextBlockOuter">
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            <td valign=3D"top" class=3D"mcnTextBlockInner" style=3D"paddin=
g-top: 9px;mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-webki=
t-text-size-adjust: 100%;">
              =09
=09=09=09
=09=09=09=09
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;" width=3D"100%" class=3D"mcnTextContent=
Container">
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<span style=3D"color:#00497E"><span style=3D"f=
ont-size:13px"><strong>Alix Coste=2C PhD=2C FAMH</strong></span></span><br=
>
<span style=3D"font-size:12px">Clinical microbiologist=2C<br>
University hospital Lausanne</span>
                        </td>
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=09=09=09=09

=09=09=09=09
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tyle=3D"background:#ffffff none no-repeat center/cover;mso-line-height-rul=
e: exactly;-ms-text-size-adjust: 100%;-webkit-text-size-adjust: 100%;backg=
round-color: #ffffff;background-image: none;background-repeat: no-repeat;b=
ackground-position: center;background-size: cover;border-top: 0;border-bot=
tom: 0;padding-top: 9px;padding-bottom: 9px;"><table border=3D"0" cellpadd=
ing=3D"0" cellspacing=3D"0" width=3D"100%" class=3D"mcnTextBlock" style=3D=
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t-text-size-adjust: 100%;">
              =09
=09=09=09
=09=09=09=09
                <table align=3D"left" border=3D"0" cellpadding=3D"0" cells=
pacing=3D"0" style=3D"max-width: 100%;min-width: 100%;border-collapse: col=
lapse;mso-table-lspace: 0pt;mso-table-rspace: 0pt;-ms-text-size-adjust: 10=
0%;-webkit-text-size-adjust: 100%;" width=3D"100%" class=3D"mcnTextContent=
Container">
                    <tbody><tr>

<span style=3D"font-family:arial=2Chelvetica n=
eue=2Chelvetica=2Csans-serif"><span style=3D"font-size:14px">The global bu=
rden of candidiasis remains relatively stable. However=2C the epidemiology=
 of the last ten years shows a shift from a majority of&nbsp;<em>Candida a=
lbicans</em>&nbsp;infections to non-albicans species. Species such as&nbsp=
;<em>C. glabrata</em>=2C&nbsp;<em>C. parapsilosis</em>&nbsp;or&nbsp;<em>C.=
 tropicalis</em>=2C not to mention&nbsp;<em>C. auris</em>=2C are increasin=
gly reported and are among the most prevalent species in some countries. T=
hese species are known to be naturally less sensitive to antifungal drugs=
 or to rapidly acquire resistance. Therefore=2C reliable antifungal suscep=
tibility testing (AFST) is essential to address the threat of antifungal r=
esistance and improve patient outcomes.<br>
&nbsp;<br>
CLSI and EUCAST offer different AFST protocols and interpretive criteria f=
or detecting antifungal resistance or at least decreased antifungal suscep=
tibility. However=2C both reference methods are labor intensive=2C making=
 them difficult to implement in a routine laboratory. In contrast=2C comme=
rcial broth microdilution (BMD) methods offer a simpler and easier-to-impl=
ement alternative. MICRONAUT-AM (Bruker Daltonics GmbH &amp; Co. KG.) is a=
 BMD solution based on the EUCAST protocol and interpreted according to EU=
CAST criteria=2C whereas Sensititre=E2=84=A2 YeastOne=E2=84=A2 (Thermo Fis=
her Scientific) follows the CLSI protocol and interpretations=2C making it=
 difficult to compare the results of both products. To overcome the differ=
ences between EUCAST and CLSI=2C a comparative evaluation of the MICRONAUT=
-AM test system using antifungal resistance genes was performed at CHUV La=
usanne=2C Switzerland. The results=2C findings and conclusions of the stud=
y will be presented in this webinar by Dr. Alix Coste=2C PhD=2C Clinical M=
icrobiologist=2C expert in mycology.<br>
&nbsp;<br>
<strong>Learning Objectives</strong></span></span>

<ul>
=09<li style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;"><span style=3D"font-family:arial=2Chelveti=
ca neue=2Chelvetica=2Csans-serif"><span style=3D"font-size:14px">Understan=
d the difference between CLSI and EUCAST AFST</span></span></li>
=09<li style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;"><span style=3D"font-family:arial=2Chelveti=
ca neue=2Chelvetica=2Csans-serif"><span style=3D"font-size:14px">Identify=
 the benefits of MICRONAUT-AM</span></span></li>
=09<li style=3D"mso-line-height-rule: exactly;-ms-text-size-adjust: 100%;-=
webkit-text-size-adjust: 100%;"><span style=3D"font-family:arial=2Chelveti=
ca neue=2Chelvetica=2Csans-serif"><span style=3D"font-size:14px">Learn abo=
ut the performance of MICRONAUT-AM</span></span></li>
</ul>
<span style=3D"font-family:arial=2Chelvetica neue=2Chelvetica=2Csans-serif=
"><span style=3D"font-size:14px">&nbsp;</span><span style=3D"font-size:12p=
x">Please contact your local representative for availability in your count=
ry. Not for sale in the USA.</span></span>
                        </td>
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                </tbody></table>
=09=09=09=09

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it-text-size-adjust: 100%;">
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e-adjust: 100%;-webkit-text-size-adjust: 100%;">
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eet</a>
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