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Subject: =?utf-8?Q?Discover=20GMP=2Dgrade=20Cas9=20protein?=
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Date: Tue, 26 Apr 2022 21:02:39 +0000
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Discover the first GMP-grade Cas9 protein designed for cell therapy: CTS=
=E2=84=A2 TrueCut=E2=84=A2 Cas9 Protein. (https://www.thermofisher.com/us/=
en/home/life-science/genome-editing/geneart-crispr/crispr-protein/cts-cas9=
=2Ehtml?CID=3D%%MAILING_NAME%%&EMID=3D%%EMAIL%%)
Having trouble viewing this email? Click here. (https://mailchi.mp/labroot=
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_lar_te_awa_el_s00_20220426) Applications & Techniques (https://www.thermo=
fisher.com/us/en/home/applications-techniques.html?CID=3Dbid_clb_gme_r01_c=
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Find out more (https://www.thermofisher.com/us/en/home/life-science/genome=
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Unlock consistently high editing efficiency for clinical research

As you move your genome editing research to clinical settings=2C high=E2=
=80=91quality ancillary materials and documentation are critical. As a rec=
ognized cell therapy supplier with CRISPR=E2=80=91Cas9 genome editing expe=
rtise=2C Thermo Fisher Scientific has developed a GMP=E2=80=91grade Cas9 p=
rotein for clinical research.

Gibco=E2=84=A2 CTS=E2=84=A2 TrueCut=E2=84=A2 Cas9 Protein (https://www.the=
rmofisher.com/us/en/home/life-science/genome-editing/geneart-crispr/crispr=
-protein/cts-cas9.html?CID=3Dbid_clb_gme_r01_co_cp1497_pjt8452_em5089171_0=
db_lar_te_awa_el_s00_20220426) has been designed to provide consistently h=
igh editing efficiency in all tested cell lines=2C including >90% editing=
 efficiency in primary T cells. It has been manufactured in compliance wit=
h standards for Ancillary Materials for Cell=E2=80=91=2C Gene=E2=80=91=2C=
 and Tissue=E2=80=91Based Products=2C which includes the following added b=
enefits:
* Traceability documentation=E2=80=94including Drug Master Files and count=
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xins=2C mycoplasma=2C residual nucleic acids=2C and proteins
* Aseptic manufacturing=E2=80=94entire process completed using single=E2=
=80=91use technology
* Sterile filling=E2=80=94finished product is added to vials in a Class A/=
B (Class 100 and ISO 5 equivalent) cleanroom

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                                        Unlock consistently high editing e=
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                                       As you move your genome editing res=
earch to clinical settings=2C high&#8209;quality ancillary materials and d=
ocumentation are critical. As a recognized cell therapy supplier with CRIS=
PR&#8209;Cas9 genome editing expertise=2C Thermo Fisher Scientific has dev=
eloped a GMP&#8209;grade Cas9 protein for clinical&nbsp;research.
=09=09=09=09=09=09=09=09=09=09<br><br>
=09=09=09=09=09=09=09=09=09=09<a href=3D"https://labroots.us7.list-manage.=
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><strong>Gibco&trade; CTS&trade; TrueCut&trade; Cas9 Protein</strong></a>=
 has been designed to provide consistently high editing efficiency in all=
 tested cell lines=2C including &gt;90% editing efficiency in primary T ce=
lls. It has been manufactured in compliance with standards for <em>Ancilla=
ry Materials for Cell&#8209;=2C Gene&#8209;=2C and Tissue&#8209;Based Prod=
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=09=09=09=09=09=09=09=09=09=09</li>
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ual nucleic acids=2C and&nbsp;proteins
=09=09=09=09=09=09=09=09=09=09</li>
=09=09=09=09=09=09=09=09=09=09<li><strong>Aseptic manufacturing</strong>&m=
dash;entire process completed using single&#8209;use&nbsp;technology
=09=09=09=09=09=09=09=09=09=09</li>
=09=09=09=09=09=09=09=09=09=09<li><strong>Sterile filling</strong>&mdash;f=
inished product is added to vials in a Class A/B (Class 100 and ISO 5 equi=
valent)&nbsp;cleanroom
=09=09=09=09=09=09=09=09=09=09</li>
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